Review Article
Plant Sources, Extraction Methods, and Uses of Squalene
Table 2
Content of fatty acids and squalene in different sources naturally extracted with various extraction methods.
| Source | Fatty acids (% w/w) | MI | Squalene | Extraction method | Reference | 16 : 0 | 18 : 0 | 18 : 1 | 18 : 2 | (% p/p) | (mg/100 g oil) |
| Vegetable | | | | | | | | | Olive | 44.0 | 4.0 | 39.0 | 11.0 | 0.7 | 150–747 | DI, DD, P | [67–69] | Amaranth | 22.0–42.0 | 2.7–3.5 | 29.0 | 7.5–45.0 | 5.9 | 6000–8000 | DI, ScCO2 | [70–73] | Seed of grape | 6.2–8.2 | 3.6–5.2 | 12.7–18.4 | 67.5–73.2 | 0.2–0.3 | 2.7–14.1 | DI, ScCO2 | [74–76] | Pistachio | — | — | — | — | — | 1.1–2.2 | DI | [77] | Walnuts, macadamia | 5.8–8.3 | 2.7–3.4 | 65.1–79.3 | 2.3–10.3 | <1.0 | 0.9–18.6 | — | [74, 78] | Peanuts | 11.1 | 2.6 | 38.4 | 44.6 | — | 9.8 | DI | [78] | Maize oil | 10.4 | 1.9 | 27.5 | 57.2 | 0.9 | 10–27 | — | [79] | Sunflower oil | — | — | — | — | 5.1–7.1 | 2.2–2.6 | DD | [80] | Palm oil | 35.0–38.0 | 10.0–11.0 | 48.0–50.0 | — | 1.9 | 0.1–1300 | ScCO2, DD | [81–83] | Soybean | 10.5 | 3.9 | 23.3 | 53.0 | 0.4–7.7 | 1.2–180 | DI, DD | [84] |
| Animal | | | | | | | | | Shark (liver oil) | 15.1–15.9 | — | 23.7–27.7 | 0.2–1.9 | 16.4 | 2300–8,400 | DI | [85–87] |
| Yeast and fungi | | | | | | | | | Saccharomyces cereviceae | — | — | — | — | — | 40 | — | [1, 29, 88] | Auranthiochytrium sp. | — | — | — | — | — | 900–6940 | DI | Pseudozyma sp. | — | — | — | — | — | 340.5 | — |
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MI: unsaponifiable matter, ScCO 2: CO 2 extraction as supercritical fluid, DI: solvent extraction, DD: deodorization distillate, P: pressure extraction, ( ) mg/g dry biomass, and ( ) mg/L. |