New Modified UPLC/Tandem Mass Spectrometry Method for Determination of Risperidone and Its Active Metabolite 9-Hydroxyrisperidone in Plasma: Application to Dose-Dependent Pharmacokinetic Study in Sprague-Dawley Rats

Figure 2

Mass spectra and the proposed patterns of fragmentation of (a) RIS, (b) 9-OH-RIS, and (c) OLA (IS).

(a)

(b)

(c)