New Modified UPLC/Tandem Mass Spectrometry Method for Determination of Risperidone and Its Active Metabolite 9-Hydroxyrisperidone in Plasma: Application to Dose-Dependent Pharmacokinetic Study in Sprague-Dawley Rats

Table 4

Recovery data of RIS 9-OH-RIS (3 QC samples) and olanzapine.

Compound	Nominal conc. (ng/mL)	Recovery (% )
RIS (analyte)	2.0	68.96
	20.0	71.51
	400.0	69.56
9-OH-RIS (metabolite)	2.0	70.29
	20.0	65.99
	400.0	67.55
Olanzapine (IS)	1200.0	68.90