Validation of a Liquid Chromatography-Tandem Mass Spectrometric Assay for Quantitative Analysis of Lenvatinib in Human Plasma

Figure 2

MRM chromatograms of the specimens. Representative MRM chromatograms of (b) lenvatinib (LOD; 0.96 ng/mL), (c) lenvatinib (LLOQ; 9.6 ng/mL), (e) propranolol as an internal standard, (a), (d) blank samples (plasma), and (f) zero sample (blank sample spiked with internal standard).

(a)

(b)

(c)

(d)

(e)

(f)