In Vitro Dissolution Profile of Dapagliflozin: Development, Method Validation, and Analysis of Commercial Tablets

Table 3

Robustness test (Factorial analysis 2³) of the analytical method for the in vitro dissolution of dapagliflozin.

pH of the medium	NaCl concentration (g)	Volume of medium (mL)	Drug released after 30 mim (%)
1.00	2.10	850	100.00
1.40	1.90	850	101.53
1.40	1.90	950	98.47
1.00	1.90	950	100.00
1.40	2.10	850	101.53
1.40	2.10	950	99.23
1.00	2.10	950	96.93
1.00	1.90	850	98.08
1.20	2.00	900	101.15
1.20	2.00	900	99.23
1.20	2.00	900	100.77