Determination of Ten Corticosteroids in Illegal Cosmetic Products by a Simple, Rapid, and High-Performance LC-MS/MS Method

Table 4

Validation data of precision and accuracy for samples containing spiked standard solutions in blank cosmetic preparations. RSD (%) = (SD/mean ) × 100. Accuracy (Bias%) = [()/] × 100.

Steroids	Intraday analysis						Interday analysis
	Precision			Accuracy			Precision			Accuracy
	0.5	1.0	1.5	0.5	1.0	1.5	0.5	1.0	1.5	0.5	1.0	1.5
CLP	2.8	4.2	3.9	1.0	1.2	0.9	3.4	5.1	4.8	0.9	1.0	1.1
DEX	3.1	4.1	6.1	2.8	2.4	2.1	4.2	5.3	6.9	1.9	1.8	2.4
MPD	3.5	2.3	2.3	4.4	3.8	3.7	3.9	2.9	3.1	4.2	3.8	3.6
PDL	2.6	3.4	2.4	1.2	1.4	1.2	2.1	3.9	2.9	1.8	1.5	1.1
FLA	5.1	4.0	5.7	2.0	1.7	1.5	4.7	4.5	6.1	1.9	1.7	1.1
FLM	4.0	3.5	2.6	2.7	1.8	1.9	5.2	4.7	4.5	1.9	1.8	1.9
PDN	4.7	4.3	3.3	2.6	2.3	2.2	5.1	4.7	3.1	3.1	2.8	2.2
TRM	2.9	3.9	2.6	3.4	2.8	2.2	3.3	4.2	3.8	3.8	3.8	4.2
TRA	5.2	4.9	4.8	0.8	0.9	1.0	5.9	6.1	6.2	1.2	1.4	1.1
BCL	6.1	5.9	5.6	6.0	5.4	5.2	6.5	6.3	6.8	4.5	6.1	5.0