Research Article

Multiparametric Magnetic Resonance Imaging and Magnetic Resonance Elastography to Evaluate the Early Effects of Bariatric Surgery on Nonalcoholic Fatty Liver Disease

Table 2

MRI and MRE measurements of study participants at baseline and during the immediate (1 month) and late (6 months) postsurgery periods.

BaselineImmediate postsurgeryLate postsurgery value (immediate postsurgery vs. baseline) value (late postsurgery vs. baseline) value (overall)

PDFF (%)0.01590.00180.0005
T2 (ms)0.08100.03550.0005
cT1 (ms)0.04730.07220.0361
MRE LSM (kPa)0.67160.97690.8228
VAT (cm2)0.00210.00060.0001
SAT (cm2+)0.39330.02560.0104
SMI<0.00010.00020.0001

MRE: magnetic resonance elastography; PDFF: proton density fat fraction; cT1: iron-corrected T1. Statistical analyses were performed using repeated measure ANOVA. Postsurgery values in the immediate and late postsurgery period were compared to the baseline using Dunnett’s test for multiple comparisons. is considered statistically significant. +Subcutaneous adipose tissue could not be measured for four subjects as tissue volume exceeded the region of measurement.