Class-Specific Histone Deacetylase Inhibitors Promote 11-Beta Hydroxysteroid Dehydrogenase Type 2 Expression in JEG-3 Cells

Figure 2

Epigenetic regulation of 11β-HSD2 expression. Graphical representation of (a) 11β-HSD2 and (b) AcH3 expression in JEG-3 cells treated with 0–10 μM of SAHA for 24 h. Data are expressed as mean ± SEM. (c) Representative photomicrographs of JEG-3 cells immunocytochemically stained for 11β-HSD2 (, compared to 0 μM; (a) one-way ANOVA with post hoc Tukey’s and (b) unpaired Student’s -test; 25 cells per group per experiment; ). Scale bar = 50 μm.

(a)

(b)

(c)