International Journal of Cell Biology

Cell Adhesion in Cancer


Publishing date
01 Apr 2012
Status
Published
Submission deadline
01 Oct 2011

Lead Editor

1Department of Life Sciences, Ewha Womans University, Seoul 120-750, Republic of Korea

2Division of Cancer Cell Research, Institute of Medical Science, University of Tokyo, Tokyo, Japan

3Department of Gynecology and Obstetrics, Medical Center, University of Münster, Münster, Germany

4Department of Biochemistry and Molecular Biology, Louisiana State University, Health Sciences Center, Shreveport, LA 71130, USA


Cell Adhesion in Cancer

Description

During cancer progression, cells lose their original tissue contacts, move through the extracellular matrix (ECM), enter into the lymphatic and/or blood system, extravasate, and subsequently form new tumors. Therefore, tumor cells inevitably experience alterations in cell–cell and cell–ECM adhesion, and the transformation activities of tumor cells are highly influenced by cell adhesion via adhesion receptors such as cadherins, integrins, cell surface proteoglycans, and tetraspanins. These adhesion receptors together with extracellular ligands in the tumor–microenvironment couple the extracellular environment to intracellular signals to enhance cancer cell migration, invasion, proliferation, and survival. Therefore, an understanding of ‘cell adhesion in cancer’ is key to understanding the development of cancer and may provide a cure for cancer in the near future.

In this special issue, we invite authors to present original research as well as review articles that will highlight the current aspects of cell adhesion signaling and stimulate the continuing efforts to understand underlying regulatory mechanism in cancer cell adhesion. Potential topics include, but are not limited to:

  • Changes in cell adhesion during epithelial to mesenchymal transition
  • Role of tumor–microenvironment during cancer progression
  • The turnover of the ECM during cancer progression
  • Tumor microenvironment and cell adhesion receptor–mediated cell adhesion signaling
  • Physical and functional cooperation between cell adhesion receptors and other cell surface receptors
  • Influences of stromal cell on cancer cell adhesion
  • Latest technologies for measuring cancer cell adhesion and migration
  • Recent advances in adhesion–based cancer therapy

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ijcb/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 965618
  • - Editorial

Cell Adhesion in Cancer

Eok-Soo Oh | Motoharu Seiki | ... | Jun Chung
  • Special Issue
  • - Volume 2012
  • - Article ID 189521
  • - Review Article

Plakoglobin: Role in Tumorigenesis and Metastasis

Zackie Aktary | Manijeh Pasdar
  • Special Issue
  • - Volume 2012
  • - Article ID 723419
  • - Review Article

Prostaglandins in Cancer Cell Adhesion, Migration, and Invasion

David G. Menter | Raymond N. DuBois
  • Special Issue
  • - Volume 2012
  • - Article ID 306879
  • - Review Article

Anoikis Resistance: An Essential Prerequisite for Tumor Metastasis

Yong-Nyun Kim | Kyung Hee Koo | ... | Hyeryeong Kim
  • Special Issue
  • - Volume 2012
  • - Article ID 676731
  • - Review Article

Cancer Cell Adhesion and Metastasis: Selectins, Integrins, and the Inhibitory Potential of Heparins

Gerd Bendas | Lubor Borsig
  • Special Issue
  • - Volume 2012
  • - Article ID 853703
  • - Review Article

Integrins and Their Extracellular Matrix Ligands in Lymphangiogenesis and Lymph Node Metastasis

Jie Chen | J. Steven Alexander | A. Wayne Orr
  • Special Issue
  • - Volume 2012
  • - Article ID 310616
  • - Review Article

Turnover of Focal Adhesions and Cancer Cell Migration

Makoto Nagano | Daisuke Hoshino | ... | Motoharu Seiki
  • Special Issue
  • - Volume 2012
  • - Article ID 340296
  • - Review Article

The Role of Immunoglobulin Superfamily Cell Adhesion Molecules in Cancer Metastasis

Chee Wai Wong | Danielle E. Dye | Deirdre R. Coombe
  • Special Issue
  • - Volume 2012
  • - Article ID 219196
  • - Review Article

Alterations in Cell-Extracellular Matrix Interactions during Progression of Cancers

Rajeswari Jinka | Renu Kapoor | ... | Gopal Pande
  • Special Issue
  • - Volume 2012
  • - Article ID 763283
  • - Review Article

The Role of Lipid Rafts in Cancer Cell Adhesion and Migration

Toshiyuki Murai
International Journal of Cell Biology
 Journal metrics
Acceptance rate11%
Submission to final decision65 days
Acceptance to publication109 days
CiteScore8.500
Impact Factor-
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