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International Journal of Endocrinology
Volume 2013 (2013), Article ID 428542, 4 pages
Clinical Study

Hepatic Steatosis, Carbohydrate Intake, and Food Quotient in Patients with NAFLD

1Pôle Hépatogastroentérologie, Endocrinologie et Nutrition, CHU de Bordeaux, Avenue de Magellan, 33600 Pessac, France
2Service de Pathologie, CHU de Bordeaux, France
3INSERM, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique, 33000 Bordeaux, France

Received 11 January 2013; Accepted 12 April 2013

Academic Editor: Kaori Minehira

Copyright © 2013 Concepcion Gonzalez et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Is steatosis related to the spontaneous carbohydrate intake in patients with NAFLD? We performed dietary records for 24 patients with NAFLD, 3 months after their liver biopsy was performed and before the deliverance of a dietary advice. The food quotient, indicator of the proportion of calories from carbohydrates, was calculated as (1.00×%  calories from carbohydrates/100) + (0.70×%  calories from lipids/100) + (0.81×%  calories from proteins/100). The associations between diet variables and steatosis% on the hepatic biopsies were tested by regression analysis, and diet variables were compared according to the presence of fibrosis. The subjects displayed a large range of steatosis, 50.5% ± 25.5 [10–90], correlated with their energy intake (1993 ± 597 kcal/d, , ) and food quotient (0.85 ± 0.02, , ), which remained significant with both variables by a multivariate regression analysis ( , ). For the 17/24 patients with a hepatic fibrosis, the energy intake was lower (fibrosis: 1863 ± 503 versus others: 2382 ± 733 kcal/d, ), and their food quotients did not differ from patients without fibrosis. Hepatic steatosis was related to the energy and carbohydrate intakes in our patients; the role of dietary carbohydrates was detectable in the range of usual carbohydrate intake: 32% to 58% calories.