Two Novel CYP11B1 Gene Mutations in Patients from Two Croatian Families with 11β-Hydroxylase Deficiency

Table 3

In silico prediction of the effects of the p.R141Q mutation in CYP11B1 function.

Prediction software	Score	Prediction of Effects of Mutation
PolyPhen-2 (http://genetics.bwh.harvard.edu/pph2)	1.000	Probably Damaging
SIFT (http://sift.jcvi.org)	0.000	Damaging
Provean (http://provean.jcvi.org)	−3.769	Deleterious