International Journal of Endocrinology / 2015 / Article / Tab 1

Clinical Study

Long-Term Effect of Surgery in Graves’ Disease: 20 Years Experience in a Single Institution

Table 1

Clinical characteristics of Graves’ disease patients who underwent surgery during the study period.

Clinical characteristicsAll Subtotal thyroidectomyTotal thyroidectomy
( = 350)( = 254)( = 96)
%%%

Gender
 Female27077.0%18572.8%8588.5%
 Male8022.9%6927.2%1111.5%
Age at surgery (year): median, IQR30(24, 39)28(23, 34)39(31.3, 50)
Resected thyroid weight (gram): median, range70.6(12.0–361.0)84.9(13.8–361.0)32.5(12.0–160.0)
Follow-up duration after surgery (month): median, IQR61(24, 103.3)57(23, 107)63.5(28.3, 91.8)
Ophthalmopathy
 No25974.0%18070.9%7982.3%
 Yes9126.0%7429.1%1717.7%
Reasons for surgery
 Resistance to ATD19555.7%17970.5%1616.7%
 Symptomatic large goiter246.9%228.7%22.1%
 Suspicious undetermined mass216.0%124.7%99.4%
 Suspicion of malignancy6719.1%06769.8%
 Patient’s desire339.4%3112.2%22.1%
 Others (not described)102.90%103.9%0
Incidence of thyroid carcinoma presented7922.6%52.0%7477.1%
Papillary thyroid carcinoma size (cm): median, range0.83(0.2–5.2)0.38(0.3–0.5)0.88(0.2–5.2)

IQR: interquartile range; ATD: antithyroid hormone drug.
All the thyroid carcinomas presented in Graves’ disease were papillary thyroid carcinomas.

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