Research Article

Optimization of Saffron Essential Oil Nanoparticles Using Chitosan-Arabic Gum Complex Nanocarrier with Ionic Gelation Method

Table 3

Experimental design with coded factor levels of independent variables and predicted values of responses.

RunLWCS (%)Arabic gum (%)Ratio (oil: AG/LWCS)-average (nm)PDIZeta potential (mV)

1(0)(1)(1)22.20.52-12
2(-1)(-1)(0)18.330.607-15.2
3(1)(0)(-1)17.140.588-14.8
4(0)(0)(0)18.70.586-15.3
5(0)(0)(0)16.240.495-15.8
6(1)(0)(1)17.040.508-14.5
7(-1)(0)(1)17.250.57-15.3
8(-1)(1)(0)17.140.503-14.8
9(0)(1)(-1)19.860.532-15.3
10(1)(-1)(0)23.380.521-12.2
11(0)(-1)(-1)19.690.523-14.2
12(0)(0)(0)16.760.503-14.8
13(0)(-1)(1)17.680.52-14
14(-1)(0)(-1)17.990.536-14.4
15(1)(1)(0)17.590.508-14.6