International Journal of Genomics

Drug-Related Genomics in Cancer and Immunological Diseases


Status
Published

Lead Editor

1Research Division of Clinical Pharmacology, First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, Jiangsu 210029, China

2State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan 650201, China

3Institut Pasteur of Shanghai, Chinese Academy of Sciences, No. 411, Hefei Road South, Shanghai 200025, China

4Department of Pharmacology, First Faculty of Medicine, Charles University in Prague, Albertov 4, 12800 Prague, Czech Republic


Drug-Related Genomics in Cancer and Immunological Diseases

Description

Drug-related genes are defined as the genes which encode enzymes, transporters, and targets related to drug absorption, distribution, metabolism, and excretion. The specific topic drug-related genomics in cancer and immunological diseases includes three fields: (1) comparative genomics and molecular evolution study on drug-related genes; (2) pharmacogenomics study on the relationship between drug-related genes mutations and drug effect or safety in the body; (3) the relationship between drug-related genes mutations and human disease susceptibility, diagnosis, development, and prognosis. Cancer is commonly defined as a “disease of the genes,” which is a failure of tissue growth regulation. Immunological diseases such as allergy and autoimmune diseases are also associated with cells and molecules genomics disorder such as disorder of NK cells, mast cells, and cytokines. The studies on drug-related genomics in cancer and immunological diseases could enhance the understanding of the role of drug-related genes in the occurrence and development of cancer or immunological diseases. Pharmacogenomics research can help clinicians predict the efficacy of drugs in the body and avoid some side effects.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand those drug-related genes and their relationship with drug response. Potential topics include, but are not limited to:

  • Comparative genomics and biological evolution of drug-related genes
  • Pharmacogenomics of drug-related enzymes, transporters, and targets involved in drug absorption, distribution, metabolism, and excretion
  • Polymorphisms of drug-related genes with human disease susceptibility, diagnosis, development, and prognosis

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/ijg/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/ijg/dodi/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 306980
  • - Editorial

Drug-Related Genomics in Cancer and Immunological Diseases

Ji-Fu Wei | Yong-Qing Wang | Huai-Rong Luo
  • Special Issue
  • - Volume 2014
  • - Article ID 312130
  • - Research Article

High Expression of Polo-Like Kinase 1 Is Associated with Early Development of Hepatocellular Carcinoma

Wei Sun | Qi Su | ... | Baolin Liu
  • Special Issue
  • - Volume 2014
  • - Article ID 870597
  • - Research Article

Genetic Variations of Cytokines and Cytokine Receptors in Psoriasis Patients from China

Xiao-Lan Li | Chun-Feng Wu | Gui-Sheng Wu
  • Special Issue
  • - Volume 2014
  • - Article ID 483905
  • - Research Article

In Silico Prediction of T and B Cell Epitopes of Der f 25 in Dermatophagoides farinae

Xiaohong Li | Hai-Wei Yang | ... | Ji-Fu Wei
  • Special Issue
  • - Volume 2014
  • - Article ID 612972
  • - Review Article

Association between NFKB1 −94ins/del ATTG Promoter Polymorphism and Cancer Susceptibility: An Updated Meta-Analysis

Xiao Yang | Pengchao Li | ... | Changjun Yin
  • Special Issue
  • - Volume 2014
  • - Article ID 950903
  • - Research Article

Upregulated PD-1 Expression Is Associated with the Development of Systemic Lupus Erythematosus, but Not the PD-1.1 Allele of the PDCD1 Gene

Qingqing Jiao | Cuiping Liu | ... | Qihong Qian
  • Special Issue
  • - Volume 2014
  • - Article ID 247637
  • - Research Article

A Promoter Region Polymorphism in PDCD-1 Gene Is Associated with Risk of Rheumatoid Arthritis in the Han Chinese Population of Southeastern China

CuiPing Liu | JueAn Jiang | ... | XueGuang Zhang
  • Special Issue
  • - Volume 2014
  • - Article ID 402603
  • - Research Article

Molecular Evolution of the Vertebrate FK506 Binding Protein 25

Fei Liu | Xiao-Long Wei | ... | Xiao-Jian Gong
International Journal of Genomics
 Journal metrics
Acceptance rate35%
Submission to final decision76 days
Acceptance to publication31 days
CiteScore3.400
Impact Factor2.414
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