Research Article
An NOS3 Haplotype Is Protective against Hypertension in a Caucasian Population
Table 2
Genotypic and allelic distributions of NOS3 polymorphisms for cases and controls.
| | Cases, n (%) | Controls, n (%) | P-value |
| | T786C | | | | | TT | 69 (30.4) | 101 (35.0) | | | TC | 118 (52.0) | 148 (51.2) | | | CC | 40 (17.6) | 40 (13.8) | .37(a) | | T alleles | 246 (55.4) | 350 (60.6) | | | C alleles | 198 (44.6) | 228 (39.4) | .12(b) |
| | Intron 4a/b | | | | | 4b/b | 165 (72.4) | 190 (62.7) | | | 4a/b | 59 (25.9) | 101 (33.3) | | | 4a/a | 4 (1.7) | 12 (4.0) | .04(a) | | b alleles | 389 (85.3) | 481 (79.4) | | | a alleles | 67 (14.7) | 125 (20.6) | .03(b) |
| | G894T | | | | | GG | 99 (43.4) | 135 (44.7) | | | GT | 95 (41.7) | 130 (43.1) | | | TT | 34 (14.9) | 37 (12.2) | .67(a) | | G alleles | 283 (63.5) | 400 (66.2) | | | T alleles | 163 (36.5) | 204 (33.8) | .39(b) |
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(a)P-value for the comparison of genotypic distribution. (b)P-value for the comparison of the allelic distribution.
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