An NOS3 Haplotype Is Protective against Hypertension in a Caucasian Population

Table 3

Unadjusted and adjusted odds ratios with the corresponding 95% confidence intervals for the association of NOS3 genotypes and hypertension: comparisons for the dominant, recessive, additive, and codominant models of the mutant alleles (786C*, 4a*, 894T*).

Polymorphism	Unadjusted	P-value	Adjusted	P-value
	OR (95% CI)		OR (95% CI)
T786C
Dominant model	1.23 (0.85–1.79)	.28	1.30 (0.64–2.63)	.47
Recessive model	1.33 (0.83–2.15)	.24	0.77 (0.33–1.83)	.56
Additive model	1.46 (0.86–2.49)	.16	0.99 (0.38–2.62)	.98
Codominant model	1.03 (0.73–1.42)	.86	1.48 (0.75–2.93)	.26
Intron 4a/b
Dominant model	0.64 (0.44–0.93)	.02	0.52 (0.26–1.04)	.06
Recessive model	0.43 (0.14–1.36)	.15	0.49 (0.08–3.07)	.45
Additive model	0.38 (0.12–1.21)	.10	0.40 (0.06–2.78)	.35
Codominant model	0.69 (0.48–1.02)	.06	0.56 (0.28–1.13)	.10
G894T
Dominant model	1.05 (0.75–1.49)	.77	1.51 (0.78–2.92)	.22
Recessive model	1.25 (0.76–2.07)	.37	1.04 (0.38–2.77)	.94
Additive model	1.25 (0.74–2.14)	.41	1.28 (0.46–3.56)	.64
Codominant model	0.94 (0.67–1.34)	.75	1.51 (0.77–2.96)	.23