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International Journal of Hypertension
Volume 2012, Article ID 192567, 9 pages
http://dx.doi.org/10.1155/2012/192567
Research Article

Differential Mechanisms of Ang (1-7)-Mediated Vasodepressor Effect in Adult and Aged Candesartan-Treated Rats

1Departments of Pharmacology, Monash University, Clayton, VIC 3800, Australia
2Departments of Physiology, Monash University, Clayton, VIC 3800, Australia

Received 29 July 2011; Accepted 7 September 2011

Academic Editor: Robson Santos

Copyright © 2012 S. Bosnyak et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [22 citations]

The following is the list of published articles that have cited the current article.

  • Tracey A. Gaspari, Antony Vinh, Emma S. Jones, and Robert E. Widdop, “Ganging up on Angiotensin II Type 1 Receptors in Vascular Remodeling,” Hypertension, vol. 60, no. 1, pp. 17–19, 2012. View at Publisher · View at Google Scholar
  • Claudia A. McCarthy, Robert E. Widdop, Kate M. Denton, and Emma S. Jones, “Update on the angiotensin AT2 receptor,” Current Hypertension Reports, vol. 15, no. 1, pp. 25–30, 2013. View at Publisher · View at Google Scholar
  • Carolyn Clarke, Monica Flores-Muñoz, Clare A. McKinney, Graeme Milligan, and Stuart A. Nicklin, “Regulation of cardiovascular remodeling by the counter-regulatory axis of the renin-angiotensin system,” Future Cardiology, vol. 9, no. 1, pp. 23–38, 2013. View at Publisher · View at Google Scholar
  • Lucinda M. Hilliard, Katrina M. Mirabito, and Kate M. Denton, “Unmasking the potential of the angiotensin AT(2) receptor as a therapeutic target in hypertension in men and women: What we know and what we still need to find out,” Clinical And Experimental Pharmacology And Physiology, vol. 40, no. 8, pp. 542–550, 2013. View at Publisher · View at Google Scholar
  • Sung-Won Jang, Sang-Hyun Ihm, Eun-Ho Choo, Ok-Ran Kim, Kiyuk Chang, Chan-Seok Park, Hee-Yeol Kim, and Ki-Bae Seung, “Imatinib Mesylate Attenuates Myocardial Remodeling Through Inhibition of Platelet-Derived Growth Factor and Transforming Growth Factor Activation in a Rat Model of Hypertension,” Hypertension, vol. 63, no. 6, pp. 1228–1234, 2014. View at Publisher · View at Google Scholar
  • Robson Augusto Santos, “Angiotensin-(1-7),” Hypertension, vol. 63, no. 6, pp. 1138–1147, 2014. View at Publisher · View at Google Scholar
  • Jiao-Lin Zheng, Guang-Ze Li, Shu-Zhen Chen, Jin-Ju Wang, James E. Olson, Hui-Jing Xia, Eric Lazartigues, Yu-Lan Zhu, and Yan-Fang Chen, “Angiotensin Converting Enzyme 2/Ang-(1-7)/Mas Axis Protects Brain from Ischemic Injury with a Tendency of Age-dependence,” CNS Neuroscience & Therapeutics, 2014. View at Publisher · View at Google Scholar
  • Clare A. McKinney, Caroline Fattah, Christopher M. Loughrey, Graeme Milligan, and Stuart A. Nicklin, “Angiotensin-(1–7) and angiotensin-(1–9): function in cardiac and vascular remodelling,” Clinical Science, vol. 126, no. 12, pp. 815–827, 2014. View at Publisher · View at Google Scholar
  • Daniel Villela, Julia Leonhardt, Neal Patel, Jason Joseph, Sebastian Kirsch, Anders Hallberg, Thomas Unger, Michael Bader, Robson A. Santos, Colin Sumners, and U. Muscha Steckelings, “ Angiotensin type 2 receptor (AT 2 R) and receptor Mas: a complex liaison ,” Clinical Science, vol. 128, no. 4, pp. 227–234, 2014. View at Publisher · View at Google Scholar
  • Robson Augusto Santos, “Angiotensin-(1-7),” Hypertension, vol. 63, no. 6, pp. 1138–1147, 2014. View at Publisher · View at Google Scholar
  • Mark C. Chappell, Allyson C. Marshall, Ebaa M. Alzayadneh, Hossam A. Shaltout, and Debra I. Diz, “Update on the angiotensin converting enzyme 2-angiotensin (1-7)-Mas receptor axis: Fetal programing, sex differences, and intracellular pathways,” Frontiers in Endocrinology, vol. 5, 2014. View at Publisher · View at Google Scholar
  • Yaning Zheng, Lin Tang, Wenhan Huang, Ruyu Yan, Feifeng Ren, Lei Luo, and Ling Zhang, “Anti-Inflammatory Effects of Ang-(1-7) in Ameliorating HFD-Induced Renal Injury through LDLr-SREBP2-SCAP Pathway,” Plos One, vol. 10, no. 8, 2015. View at Publisher · View at Google Scholar
  • Evelyn Mendoza-Torres, Alejandra Oyarzún, David Mondaca-Ruff, Andrés Azocar, Pablo F. Castro, Jorge E. Jalil, Mario Chiong, Sergio Lavandero, and María Paz Ocaranza, “ACE2 and vasoactive peptides: Novel players in cardiovascular/renal remodeling and hypertension,” Therapeutic Advances in Cardiovascular Disease, vol. 9, no. 4, pp. 217–237, 2015. View at Publisher · View at Google Scholar
  • Johanna Schuchard, Martina Winkler, Ines Stölting, Franziska Schuster, Florian M Vogt, Jörg Barkhausen, Christoph Thorns, Robson A Santos, Michael Bader, and Walter Raasch, “ Lack of weight gain after angiotensin AT 1 receptor blockade in diet-induced obesity is partly mediated by an angiotensin-(1-7)/Mas-dependent pathway ,” British Journal of Pharmacology, 2015. View at Publisher · View at Google Scholar
  • Kenji Shimada, Hajime Furukawa, Kosuke Wada, Yuan Wei, Yoshiteru Tada, Atsushi Kuwabara, Fumiaki Shikata, Yasuhisa Kanematsu, Michael T Lawton, Keiko T Kitazato, Shinji Nagahiro, and Tomoki Hashimoto, “Angiotensin-(1-7) protects against the development of aneurysmal subarachnoid hemorrhage in mice,” Journal of Cerebral Blood Flow & Metabolism, 2015. View at Publisher · View at Google Scholar
  • Shu-Yan Dai, Wei Peng, Yu-Ping Zhang, Jian-Dong Li, Ying Shen, and Xiao-Fei Sun, “Brain endogenous angiotensin II receptor type 2 (AT2-R) protects against DOCA/salt-induced hypertension in female rats,” Journal of Neuroinflammation, vol. 12, no. 1, 2015. View at Publisher · View at Google Scholar
  • Douglas M. Bennion, Emily Haltigan, Robert W. Regenhardt, U. Muscha Steckelings, and Colin Sumners, “Neuroprotective Mechanisms of the ACE2–Angiotensin-(1-7)–Mas Axis in Stroke,” Current Hypertension Reports, vol. 17, no. 2, 2015. View at Publisher · View at Google Scholar
  • Melvin D. Lobo, Paul A. Sobotka, and Atul Pathak, “Interventional procedures and future drug therapy for hypertension,” European Heart Journal, pp. ehw303, 2016. View at Publisher · View at Google Scholar
  • Katrina M. Mirabito Colafella, Kate M. Denton, and Lucinda M. Hilliard, “Epochs in the depressor/pressor balance of the renin-angiotensin system,” Clinical Science, vol. 130, no. 10, pp. 761–771, 2016. View at Publisher · View at Google Scholar
  • Julia Leonhardt, Verena Benz, Natalia Alenina, Nicholas Daniell, Masatsugu Horiuchi, Masaru Iwai, Gerhard Multhaup, Ralf Schülein, Michael Bader, Robson A. Santos, Thomas Unger, Daniel C. Villela, Ulrike Muscha Steckelings, Anke Teichmann, Lisa-Marie Münter, Magnus C. Mayer, Maibritt Mardahl, Sebastian Kirsch, Pawel Namsolleck, and Kristin Lucht, “Evidence for Heterodimerization and Functional Interaction of the Angiotensin Type 2 Receptor and the Receptor MAS,” Hypertension, vol. 69, no. 6, pp. 1128–1135, 2017. View at Publisher · View at Google Scholar
  • Mariam H.M. Yousif, Ibrahim F. Benter, Debra I. Diz, and Mark C. Chappell, “Angiotensin-(1-7)-Dependent Vasorelaxation Of The Renal Artery Exhibits Unique Angiotensin And Bradykinin Receptor Selectivity,” Peptides, 2017. View at Publisher · View at Google Scholar
  • Sanket N Patel, Quaisar Ali, Preethi Samuel, Ulrike Muscha Steckelings, and Tahir Hussain, “Angiotensin II Type 2 Receptor and Receptor Mas Are Colocalized and Functionally Interdependent in Obese Zucker Rat Kidney.,” Hypertension (Dallas, Tex. : 1979), vol. 70, no. 4, pp. 831–838, 2017. View at Publisher · View at Google Scholar