Table of Contents Author Guidelines Submit a Manuscript
International Journal of Inflammation
Volume 2012, Article ID 480373, 5 pages
http://dx.doi.org/10.1155/2012/480373
Review Article

Is Still's Disease an Autoinflammatory Syndrome?

Department of Paediatrics and Paediatric Rheumatology, Bicêtre Hospital, National Reference Centre for Autoinflammatory Diseases, 78 rue du Général Leclerc, Le Kremlin Bicêtre, 94270 Paris, France

Received 23 January 2012; Revised 28 February 2012; Accepted 1 March 2012

Academic Editor: L. Nandini Moorthy

Copyright © 2012 Linda Rossi-Semerano and Isabelle Koné-Paut. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. E. Petty, T. R. Southwood, P. Manners et al., “International league of associations for rheumatology classification of juvenile idiopathic arthritis: second revision, edmonton, 2001,” Journal of Rheumatology, vol. 31, no. 2, pp. 390–392, 2004. View at Google Scholar · View at Scopus
  2. P. Quartier, P. Taupin, F. Bourdeaut et al., “Efficacy of etanercept for the treatment of juvenile idiopathic arthritis according to the onset type,” Arthritis & Rheumatism, vol. 48, no. 4, pp. 1093–1101, 2003. View at Publisher · View at Google Scholar · View at Scopus
  3. E. M. Behrens, T. Beukelman, L. Gallo et al., “Evaluation of the presentation of systemic onset juvenile rheumatoid arthritis: data from the Pennsylvania Systemic Onset Juvenile Arthritis Registry (PASOJAR),” Journal of Rheumatology, vol. 35, no. 2, pp. 343–348, 2008. View at Google Scholar · View at Scopus
  4. R. Gurion, T. J. A. Lehman, and L. N. Moorthy, “Systemic arthritis in children: a review of clinical presentation and treatment,” International Journal of Inflammation, vol. 2012, Article ID 271569, 16 pages, 2012. View at Publisher · View at Google Scholar
  5. S. L. Masters, A. Simon, I. Aksentijevich, and D. L. Kastner, “Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease,” Annual Review of Immunology, vol. 27, pp. 621–668, 2009. View at Publisher · View at Google Scholar · View at Scopus
  6. F. Luthi, P. Zufferey, M. F. Hofer, and A. K. So, ““Adolescent-onset Still's disease”: characteristics and outcome in comparison with adult-onset Still's disease,” Clinical and Experimental Rheumatology, vol. 20, no. 3, pp. 427–430, 2002. View at Google Scholar · View at Scopus
  7. E. M. Behrens, T. Beukelman, M. Paessler, and R. Q. Cron, “Occult macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis,” Journal of Rheumatology, vol. 34, no. 5, pp. 1133–1138, 2007. View at Google Scholar · View at Scopus
  8. J. Bleesing, A. Prada, D. M. Siegel et al., “The diagnostic significance of soluble CD163 and soluble interleukin-2 receptor α-chain in macrophage activation syndrome and untreated new-onset systemic juvenile idiopathic arthritis,” Arthritis & Rheumatism, vol. 56, no. 3, pp. 965–971, 2007. View at Publisher · View at Google Scholar · View at Scopus
  9. S. J. Vastert, R. van Wijk, L. E. D'Urbano et al., “Mutations in the perforin gene can be linked to macrophage activation syndrome in patients with systemic onset juvenile idiopathic arthritis,” Rheumatology, vol. 49, no. 3, pp. 441–449, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. S. Davì, A. Consolaro, D. Guseinova et al., “An international consensus survey of diagnostic criteria for macrophage activation syndrome in systemic juvenile idiopathic arthritis,” Journal of Rheumatology, vol. 38, no. 4, pp. 764–768, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. Y. T. Lin, C. T. Wang, M. E. Gershwin, and B. L. Chiang, “The pathogenesis of oligoarticular/polyarticular vs systemic juvenile idiopathic arthritis,” Autoimmunity Reviews, vol. 10, no. 8, pp. 482–489, 2011. View at Publisher · View at Google Scholar · View at Scopus
  12. V. Pascual, F. Allantaz, E. Arce, M. Punaro, and J. Banchereau, “Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade,” Journal of Experimental Medicine, vol. 201, no. 9, pp. 1479–1486, 2005. View at Publisher · View at Google Scholar · View at Scopus
  13. B. Prakken, S. Albani, and A. Martini, “Juvenile idiopathic arthritis,” The Lancet, vol. 377, no. 9783, pp. 2138–2149, 2011. View at Publisher · View at Google Scholar · View at Scopus
  14. E. D. Mellins, C. MacAubas, and A. A. Grom, “Pathogenesis of systemic juvenile idiopathic arthritis: some answers, more questions,” Nature Reviews Rheumatology, vol. 7, no. 7, pp. 416–426, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. W. De Jager, E. P. A. H. Hoppenreijs, N. M. Wulffraat, L. R. Wedderburn, W. Kuis, and B. J. Prakken, “Blood and synovial fluid cytokine signatures in patients with juvenile idiopathic arthritis: a cross-sectional study,” Annals of the Rheumatic Diseases, vol. 66, no. 5, pp. 589–598, 2007. View at Publisher · View at Google Scholar · View at Scopus
  16. F. De Benedetti, M. Massa, P. Robbioni, A. Ravelli, G. R. Burgio, and A. Martini, “Correlation of serum interleukin-6 levels with joint involvement and thrombocytosis in systemic juvenile rheumatoid arthritis,” Arthritis & Rheumatism, vol. 34, no. 9, pp. 1158–1163, 1991. View at Publisher · View at Google Scholar · View at Scopus
  17. D. Foell and J. Roth, “Proinflammatory S100 proteins in arthritis and autoimmune disease,” Arthritis & Rheumatism, vol. 50, no. 12, pp. 3762–3771, 2004. View at Publisher · View at Google Scholar · View at Scopus
  18. P. Quartier, F. Allantaz, R. Cimaz et al., “A multicentre, randomised, double-blind, placebo-controlled trial with the interleukin-1 receptor antagonist anakinra in patients with systemic-onset juvenile idiopathic arthritis (ANAJIS trial),” Annals of the Rheumatic Diseases, vol. 70, no. 5, pp. 747–754, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. T. Lequerré, P. Quartier, D. Rosellini et al., “Interleukin-1 receptor antagonist (anakinra) treatment in patients with systemic-onset juvenile idiopathic arthritis or adult onset Still disease: preliminary experience in France,” Annals of the Rheumatic Diseases, vol. 67, no. 3, pp. 302–308, 2008. View at Publisher · View at Google Scholar · View at Scopus
  20. M. Gattorno, A. Piccini, D. Lasigliè et al., “The pattern of response to anti-interleukin-1 treatment distinguishes two subsets of patients with systemic-onset juvenile idiopathic arthritis,” Arthritis & Rheumatism, vol. 58, no. 5, pp. 1505–1515, 2008. View at Publisher · View at Google Scholar · View at Scopus
  21. P. A. Nigrovic, M. Mannion, F. H. M. Prince et al., “Anakinra as first-line disease-modifying therapy in systemic juvenile idiopathic arthritis: report of forty-six patients from an international multicenter series,” Arthritis & Rheumatism, vol. 63, no. 2, pp. 545–555, 2011. View at Publisher · View at Google Scholar · View at Scopus
  22. R. Goldbach-Mansky, N. J. Dailey, S. W. Canna et al., “Neonatal-onset multisystem inflammatory disease responsive to interleukin-1β inhibition,” The New England Journal of Medicine, vol. 355, no. 6, pp. 581–592, 2006. View at Publisher · View at Google Scholar · View at Scopus
  23. N. Ruperto, P. Quartier, N. Wulffraat et al., “A phase II study to evaluate dosing and preliminary safety and efficacy of canakinumab in systemic juvenile idiopathic arthritis with active systemic features,” Arthritis & Rheumatism, vol. 64, no. 2, pp. 557–567, 2012. View at Google Scholar
  24. D. J. Lovell, E. H. Giannini, Y. Kimura et al., “Long-term safety and efficacy of rilonacept in patients with systemic juvenile idiopathic arthritis (SJIA),” Arthritis & Rheumatism, vol. 60, supplement, p. S768, 2009. View at Google Scholar
  25. F. De Benedetti and A. Martini, “Is systemic juvenile rheumatoid arthritis an interleukin 6 mediated disease?” The Journal of Rheumatology, vol. 25, no. 2, pp. 203–207, 1998. View at Google Scholar · View at Scopus
  26. J. E. Fonseca, M. J. Santos, H. Canhão, and E. Choy, “Interleukin-6 as a key player in systemic inflammation and joint destruction,” Autoimmunity Reviews, vol. 8, no. 7, pp. 538–542, 2009. View at Publisher · View at Google Scholar · View at Scopus
  27. D. Fishman, G. Faulds, R. Jeffey et al., “The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis,” Journal of Clinical Investigation, vol. 102, no. 7, pp. 1369–1376, 1998. View at Google Scholar · View at Scopus
  28. E. M. Ogilvie, M. S. Fife, S. D. Thompson et al., “The -174G allele of the interleukin-6 gene confers susceptibility to systemic arthritis in children: a multicenter study using simplex and multiplex juvenile idiopathic arthritis families,” Arthritis & Rheumatism, vol. 48, no. 11, pp. 3202–3206, 2003. View at Publisher · View at Google Scholar · View at Scopus
  29. S. Yokota, T. Imagawa, M. Mori et al., “Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled, withdrawal phase III trial,” The Lancet, vol. 371, no. 9617, pp. 998–1006, 2008. View at Publisher · View at Google Scholar · View at Scopus
  30. F. De Benedetti, H. I. Brunner, N. Ruperto et al., “Efficacy and safety of tocilizumab in patients with systemic juvenile idiopathic arthritis (sJIA): 12-week data from the phase 3 TENDER trial,” Annals of the Rheumatic Diseases, vol. 69, supplement 146, 2010. View at Google Scholar
  31. N. Maeno, S. Takei, Y. Nomura et al., “Highly elevated serum levels of interleukin-18 in systemic juvenile idiopathic arthritis but not in other juvenile idiopathic arthritis subtypes or in Kawasaki disease,” Arthritis & Rheumatism, vol. 46, no. 9, pp. 2539–2542, 2002. View at Publisher · View at Google Scholar · View at Scopus
  32. M. Kawashima, M. Yamamura, M. Taniai et al., “Levels of interleukin-18 and its binding inhibitors in the blood circulation of patients with adult-onset Still's disease,” Arthritis & Rheumatism, vol. 44, pp. 550–560, 2001. View at Google Scholar
  33. W. De Jager, S. J. Vastert, J. M. Beekman et al., “Defective phosphorylation of interleukin-18 receptor β causes impaired natural killer cell function in systemic-onset juvenile idiopathic arthritis,” Arthritis & Rheumatism, vol. 60, no. 9, pp. 2782–2793, 2009. View at Publisher · View at Google Scholar · View at Scopus