Research Article

Mathematical Model for Hepatocytic-Erythrocytic Dynamics of Malaria

Table 3

Parameter values used in the numerical simulation and demonstration of the existence of endemic equilibrium point. See Table 2 for detailed parameter descriptions.

Symbol Interpretation Value Source

Death rate of macrophages0.05/day [19]
Death rate of sporozoites /day [20]
Elimination rate of IRBCs by macrophages [19]
Recruitment rate of [21]
Production rate of due to [19]
Death rate of 0.029 /day [20]
Rate of injection of sporozoites20 sporozoites/day [20]
Production rate of RBCs due to IRBCs [19]
Hepatocyte invasion rate [20]
Immunogenicity of IRBCs [19]
Death rate of infected hepatocytes0.02/day [20]
Inhibition rate1 [22]
Recruitment rate of RBCs [23]
Merozoites that cause secondary infections0.726 (unitless) [24]
Death rate of healthy RBCs0.0083/day [23]
Inhibition rate1 [22]
Invasion rate of RBCs [23]
Merozoites per liver schizont10000/day [21]
Death rate of infected RBCs0.025/day [19]
Inhibition rate1 [22]
Death rate of merozoites48/day [23]
Merozoites per blood schizont16 [21]
Recruitment rate of macrophages30 [19]