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International Journal of Nephrology
Volume 2011, Article ID 734832, 5 pages
Review Article

Arterial Stiffness in Chronic Kidney Disease: The Usefulness of a Marker of Vascular Damage

1Division of Nephrology, S.Orsola-Malpighi Hospital, University of Bologna, 40138 Bologna, Italy
2Division of Cardiology, Ospedale di Mirandola, 41121 Modena, Italy

Received 23 March 2011; Accepted 27 March 2011

Academic Editor: Biagio Raffaele Di Iorio

Copyright © 2011 Antonio Bellasi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Increased arterial stiffness is a marker of vasculopathy in chronic kidney disease (CKD) patients, suggesting a significant cardiovascular damage. Detection of arterial stiffness provides physicians with useful prognostic information independent of traditional cardiovascular (CV) risk factors. In addition, this knowledge may help guide appropriate therapeutic choices and monitor the effectiveness of antihypertensive therapies. We review the relationship between arterial stiffness and CKD, as well as the prognostic implications of increased arterial stiffness and the potential therapeutic strategies to ameliorate arterial compliance and outcome in CKD.