Reduced Kidney Function in Tenofovir Disoproxil Fumarate Based Regimen and Associated Factors: A Hospital Based Prospective Observational Study in Ethiopian Patients

Table 6

Changing patterns of estimated glomerular filtration rate and serum creatinine over 6-month follow-up of study participants in TASH, October 2017 [n = 63].

	Months
	0	1	2	6
Mean eGFR ± SD	90.81 ± 16.8	82.46 ± 17	82.93 ± 15.3	82.44 ± 15
Mean change in eGFR ± SD; 95 CI of mean change in eGFR	-	-8.35 ± 17.5^+	-7.89 ± 15.10^+	-8.37 ± 18.4^+
	-	-12.81, -3.8	-11.70, -4.10	-13.00, -3.70
Mean SCr ± SD	1.01 ± 0.16	1.10 ± 0.19	1.09 ± 0.17	1.10 ± 0.17
Mean change in SCr ± SD; 95 CI of mean change in SCr	-	0.09 ± 0.18^+	0.08 ± 0.17^+	-0.08 ± 0.19^+
	-	0.05, 0.14	0.04, 0.12	0.04, 0.13

Note: eGFR, estimated glomerular filtration rate; SEM, standard deviation; CI, confidence interval; SCr, serum creatinine. P values by repeated measures one-way ANOVA ( stands for P < 0.05) and post hoc tests using paired t-test with Bonferroni correction (⁺ stands for P < 0.05).