Combined Application of 17-Estradiol and Progesterone Enhance Vascular Endothelial Growth Factor and Surfactant Protein Expression in Cultured Embryonic Lung Cells of Mice
Figure 5
Quantification
of VEGF protein release of lung fibroblasts treated for 48 hours with E2-8 M and P-8 M alone or in combination determined by ELISA. Note
that corresponding with results obtained by gene expression analysis (Figure 3)
VEGF protein is increased in central lung fibroblast cultures only by combined treatment
with E2 and P. Pretreatment with ICI/RU 486 abrogated this effect. control versus E2/P-8 M.
