Table of Contents Author Guidelines Submit a Manuscript
International Journal of Rheumatology
Volume 2012, Article ID 198314, 4 pages
http://dx.doi.org/10.1155/2012/198314
Review Article

The Utility of Serum IgG4 Concentrations as a Biomarker

1Center for Health, Safety, and Environmental Management, Shinshu University, 3-1-1 Asahi, Matsumoto 390-8621, Japan
2Department of Gastroenterology, School of Medicine Shinshu University, 3-1-1 Asahi, Matsumoto 390-8621, Japan
3Department of Medical Information, School of Medicine Shinshu University, 3-1-1 Asahi, Matsumoto 390-8621, Japan

Received 23 November 2011; Accepted 17 January 2012

Academic Editor: Yoh Zen

Copyright © 2012 Shigeyuki Kawa et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. Kawa and S. Sugai, “History of autoimmune pancreatitis and Mikulicz's disease,” Current Immunology Reviews, vol. 7, no. 2, pp. 137–143, 2011. View at Google Scholar
  2. S. Kawa, Y. Fujinaga, M. Ota, H. Hamano, and S. Bahram, “Autoimmune pancreatitis and diagnostic criteria,” Current Immunology Reviews, vol. 7, no. 2, pp. 144–161, 2011. View at Google Scholar
  3. H. Umehara, K. Okazaki, Y. Masaki et al., “A novel clinical entity, IgG4-related disease (IgG4RD): general concept and details,” Modern Rheumatology, vol. 22, no. 1, pp. 21–30, 2012. View at Publisher · View at Google Scholar
  4. S. Kawa, H. Hamano, and K. Kiyosawa, “Pancreatitis,” in The Autoimmune Diseases, N. Rose and I. MacKay, Eds., pp. 779–786, Academic Press, St Louis, Mo, USA, 4th edition, 2006. View at Google Scholar
  5. H. Hamano, S. Kawa, A. Horiuchi et al., “High serum IgG4 concentrations in patients with sclerosing pancreatitis,” The New England Journal of Medicine, vol. 344, no. 10, pp. 732–738, 2001. View at Publisher · View at Google Scholar · View at Scopus
  6. H. Hamano, S. Kawa, Y. Ochi et al., “Hydronephrosis associated with retroperitoneal fibrosis and sclerosing pancreatitis,” The Lancet, vol. 359, no. 9315, pp. 1403–1404, 2002. View at Publisher · View at Google Scholar · View at Scopus
  7. H. Hamano, N. Arakura, T. Muraki, Y. Ozaki, K. Kiyosawa, and S. Kawa, “Prevalence and distribution of extrapancreatic lesions complicating autoimmune pancreatitis,” Journal of Gastroenterology, vol. 41, no. 12, pp. 1197–1205, 2006. View at Publisher · View at Google Scholar · View at Scopus
  8. S. Kawa, K. Okazaki, T. Kamisawa, T. Shimosegawa, and M. Tanaka, “Japanese consensus guidelines for management of autoimmune pancreatitis: II. Extrapancreatic lesions, differential diagnosis,” Journal of Gastroenterology, vol. 45, no. 4, pp. 355–369, 2010. View at Publisher · View at Google Scholar · View at Scopus
  9. K. Okazaki, S. Kawa, T. Kamisawa et al., “Clinical diagnostic criteria of autoimmune pancreatitis: revised proposal,” Journal of Gastroenterology, vol. 41, no. 7, pp. 626–631, 2006. View at Publisher · View at Google Scholar · View at Scopus
  10. K. P. Kim, M. H. Kim, J. C. Kim, S. S. Lee, D. W. Seo, and S. K. Lee, “Diagnostic criteria for autoimmune chronic pancreatitis revisited,” World Journal of Gastroenterology, vol. 12, no. 16, pp. 2487–2496, 2006. View at Google Scholar · View at Scopus
  11. S. T. Chari, T. C. Smyrk, M. J. Levy et al., “Diagnosis of autoimmune pancreatitis: the mayo clinic experience,” Clinical Gastroenterology and Hepatology, vol. 4, no. 8, pp. 1010–1016, 2006. View at Publisher · View at Google Scholar · View at Scopus
  12. M. Otsuki, J. B. Chung, K. Okazaki et al., “Asian diagnostic criteria for autoimmune pancreatitis: consensus of the Japan-Korea symposium on autoimmune pancreatitis,” Journal of Gastroenterology, vol. 43, no. 6, pp. 403–408, 2008. View at Publisher · View at Google Scholar · View at Scopus
  13. K. Kawaguchi, M. Koike, K. Tsuruta, A. Okamoto, I. Tabata, and N. Fujita, “Lymphoplasmacytic sclerosing pancreatitis with cholangitis: a variant of primary sclerosing cholangitis extensively involving pancreas,” Human Pathology, vol. 22, no. 4, pp. 387–395, 1991. View at Publisher · View at Google Scholar · View at Scopus
  14. K. Notohara, L. J. Burgart, D. Yadav, S. Chari, and T. C. Smyrk, “Idiopathic chronic pancreatitis with periductal lymphoplasmacytic infiltration: clinicopathologic features of 35 cases,” American Journal of Surgical Pathology, vol. 27, no. 8, pp. 1119–1127, 2003. View at Publisher · View at Google Scholar · View at Scopus
  15. H. Matsubayashi, H. Sawai, H. Kimura et al., “Characteristics of autoimmune pancreatitis based on serum IgG4 level,” Digestive and Liver Disease, vol. 43, no. 9, pp. 731–735, 2011. View at Publisher · View at Google Scholar
  16. S. C. Abraham, R. E. Wilentz, C. J. Yeo et al., “Pancreaticoduodenectomy (Whipple resections) in patients without malignancy: are they all “chronic pancreatitis”?” American Journal of Surgical Pathology, vol. 27, no. 1, pp. 110–120, 2003. View at Publisher · View at Google Scholar · View at Scopus
  17. A. M. Morselli-Labate and R. Pezzilli, “Usefulness of serum IgG4 in the diagnosis and follow up of autoimmune pancreatitis: a systematic literature review and meta-analysis,” Journal of Gastroenterology and Hepatology, vol. 24, no. 1, pp. 15–36, 2009. View at Publisher · View at Google Scholar · View at Scopus
  18. E. K. Choi, M. H. Kim, T. Y. Lee et al., “The sensitivity and specificity of serum immunoglobulin G and immunoglobulin G4 levels in the diagnosis of autoimmune chronic pancreatitis: Korean experience,” Pancreas, vol. 35, no. 2, pp. 156–161, 2007. View at Publisher · View at Google Scholar · View at Scopus
  19. A. Ghazale, S. T. Chari, T. C. Smyrk et al., “Value of serum IgG4 in the diagnosis of autoimmune pancreatitis and in distinguishing it from pancreatic cancer,” American Journal of Gastroenterology, vol. 102, no. 8, pp. 1646–1653, 2007. View at Publisher · View at Google Scholar · View at Scopus
  20. M. Takayama, H. Hamano, Y. Ochi et al., “Recurrent attacks of autoimmune pancreatitis result in pancreatic stone formation,” American Journal of Gastroenterology, vol. 99, no. 5, pp. 932–937, 2004. View at Publisher · View at Google Scholar · View at Scopus
  21. K. Hirano, Y. Asaoka, M. Tada et al., “No significant relation between relapse of autoimmune pancreatitis and substitution of aspartic acid at position 57 of DQβ1,” Journal of Gastroenterology, vol. 44, no. 7, pp. 799–800, 2009. View at Publisher · View at Google Scholar · View at Scopus
  22. K. Kubota, S. Watanabe, T. Uchiyama et al., “Factors predictive of relapse and spontaneous remission of autoimmune pancreatitis patients treated/not treated with corticosteroids,” Journal of Gastroenterology, vol. 46, no. 6, pp. 834–842, 2011. View at Publisher · View at Google Scholar
  23. S. Kawa and H. Hamano, “Clinical features of autoimmune pancreatitis,” Journal of Gastroenterology, vol. 42, no. 18, pp. 9–14, 2007. View at Publisher · View at Google Scholar · View at Scopus
  24. S. Kawa, H. Hamano, Y. Ozaki et al., “Long-term follow-up of autoimmune pancreatitis: characteristics of chronic disease and recurrence,” Clinical Gastroenterology and Hepatology, vol. 7, no. 11, supplement, pp. S18–S22, 2009. View at Publisher · View at Google Scholar
  25. B. Rock, C. R. Martins, A. N. Theofilopoulos et al., “The pathogenic effect of IgG4 autoantibodies in endemic pemphigus foliaceus (fogo selvagem),” The New England Journal of Medicine, vol. 320, no. 22, pp. 1463–1469, 1989. View at Google Scholar · View at Scopus
  26. S. Aoki, T. Nakazawa, H. Ohara et al., “Immunohistochemical study of autoimmune pancreatitis using anti-IgG4 antibody and patients' sera,” Histopathology, vol. 47, no. 2, pp. 147–158, 2005. View at Publisher · View at Google Scholar · View at Scopus
  27. M. van der Neut Kolfschoten, J. Schuurman, M. Losen et al., “Anti-inflammatory activity of human IgG4 antibodies by dynamic Fab arm exchange,” Science, vol. 317, no. 5844, pp. 1554–1557, 2007. View at Publisher · View at Google Scholar · View at Scopus
  28. S. Kawa, K. Kitahara, H. Hamano et al., “A novel immunoglobulin-immunoglobulin interaction in autoimmunity,” Plos ONE, vol. 3, no. 2, Article ID e1637, 2008. View at Publisher · View at Google Scholar · View at Scopus