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Journal of Automatic Chemistry
Volume 13 (1991), Issue 2, Pages 45-47

Detection, signal processing, and calibration In lmmunoassay systems

1Istituto H.S. Raffaele, Dipartimento di Medicina di Laboratorio, Milano 20132, Italy
2Universita' di Firenze, Istituto di Endocrinologia, Firenze, Italy
3Ospedale di Careggi, Laboratorio Analisi, Firenze, Italy
4Università di Messina, Istituto di Chimica, Messina, Italy

Copyright © 1991 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The new trends in immunochemistry related to the replacement of radioisotopic labels with non-radioactive labels are presented. Immunoenzymatic, fluorescent and chemiluminescent techniques are described in terms of their basic principles and their most common applications. The advantages of computer-controlled calibration are also discussed.