Simultaneous Determination of Volatile Constituents from Acorus tatarinowii Schott in Rat Plasma by Gas Chromatography-Mass Spectrometry with Selective Ion Monitoring and Application in Pharmacokinetic Study

Table 3

Matrix effects and extraction recovery of analytes in biological samples.

Analyte	Concentration (μg/mL)	Matrix effects (%, 𝑛=6)	RSD (%)	Extraction recovery (%, 𝑛=5)	RSD (%)
Methyl eugenol	0.025	93.8 ± 5.2	5.5	105.2 ± 5.4	5.1
	0.250	94.6 ± 5.8	6.1	92.4 ± 6.2	6.7
	2.500	105.2 ± 4.7	4.5	96.5 ± 4.0	4.1
𝛽-Asarone	0.025	92.4 ± 6.6	6.5	102.9 ± 5.0	4.9
	0.250	98.6 ± 6.2	6.3	94.0 ± 6.0	6.4
	2.500	101.3 ± 3.8	3.8	95.1 ± 4.8	5.0
𝛼-Asarone	0.025	96.9 ± 4.4	4.5	99.2 ± 7.0	7.1
	0.250	100.6 ± 7.8	7.8	95.3 ± 3.1	3.3
	2.500	103.8 ± 6.2	6.0	100.7 ± 4.9	4.9
I.S.	2.0	94.1 ± 4.0	4.3	93.6 ± 3.1	8.6