Application of ¹⁹F NMR Spectroscopy for Content Determination of Fluorinated Pharmaceuticals

Table 4

Analytical results for buffer-soluble compounds.

Compound	Purity (% w/w)
	^19F NMR
Fluphenazine dihydrochloride	88.8
Fluoxetine HCl	84.0
Fludarabine phosphate	89.1
Flurazepam monohydrochloride	86.5
5-Fluorocytosine	82.8
Fluconazole	86.2
	85.9
Sodium flurbiprofen dihydrate	89.3

Comparison HPLC data or USP certificates not available for these compounds.