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| No | PDE-5i | Chemical formula | Retention time (min) | Ion type | Precursor ion (m/z) | Product ions (m/z) |
|
| 1 | Mirodenafil | C26H37N5O5S | 7.57 | M + H | 532.2588 | 99.09167; 296.13935; 312.13427; 70.06513; 56.04948; 84.0682; 210.06619; 129.10224; 88.07569; 121.03964 |
| 2 | Noracetildenafil | C24H32N6O3 | 13.96 | M + H | 453.2609 | 70.06513; 97.07602; 113.10732; 98.08385; 58.06513; 56.04948; 297.1346; 166.09749; 325.12952; 353.16082 |
| 3 | Desmethyl fondenafil | C23H30N6O3 | 15.29 | M + H | 439.2459 | 339.14505; 311.11395; 396.20255; 374.42169; 319.71493; 196.38647; 165.01724; 120.37976; 99.0919; 73.11301 |
| 4 | N-Octylnortadalafil | C29H33N3O4 | 15.64 | M + H | 489.3126 | 169.07602; 135.04406; 204.08078; 262.08626; 338.22269; 115.05423; 197.07094; 264.10191; 130.06513; 232.07569 |
| 5 | Acetylvardenafil | C25H34N6O3 | 16.01 | M + H | 467.2765 | 169.09715; 70.06513; 84.08078; 341.16082; 111.09167; 72.08078; 127.12297; 97.07602; 112.0995; 110.06004 |
| 6 | Lodenafil carbonate | C47H62N12O11S2 | 16.07 | M + H | 1048.642 | 112.0995; 82.06513; 58.06513; 97.07602; 111.09167; 56.04948; 487.2122; 83.06037; 84.08078; 283.11895 |
| 7 | Hydroxyacetildenafil | C25H34N6O4 | 16.13 | M + H | 483.2714 | 97.07602; 70.06513; 127.08659; 143.11789; 100.07569; 297.1346; 88.07569; 166.09749; 112.0995; 128.09441 |
| 8 | Carbodenafil | C24H32N6O3 | 16.23 | M + H | 453.2609 | 311.11387; 339.14517; 166.09749; 255.12404; 69.04472; 97.07602; 225.07709; 70.06513 |
| 9 | Acetildenafil | C25H34N6O3 | 16.48 | M + H | 467.2765 | 111.09167; 97.07602; 70.06513; 84.08078; 72.08078; 127.12297; 112.0995; 297.1346; 56.04948; 166.09749 |
| 10 | Descarbonsildenafil | C21H30N6O4S | 16.59 | M + H | 463.2129 | 418.15475; 311.15069; 432.17177; 406.15494; 361.13279; 344.14795; 283.11908; 238.83536; 192.99106; 175.69979; 151.05383; 125.02768; 87.09227; 72.08158; 58.066 |
| 11 | Piperiacetildenafil | C24H31N5O3 | 16.75 | M + H | 438.25 | 98.09643; 70.06513; 297.1346; 55.05423; 166.09749; 341.16082; 69.04472; 325.12952; 86.09643 |
| 12 | Dimethylacetildenafil | C25H34N6O3 | 16.96 | M + H | 467.2765 | 84.08078; 127.12297; 112.0995; 111.09167; 70.06513; 297.1346; 58.06513; 166.09749; 325.1659; 410.21867 |
| 13 | Hydroxyvardenafil | C23H32N6O5S | 17.09 | M + H | 505.2228 | 169.09715; 344.14791; 99.09167; 110.06004; 299.11387; 123.09167; 58.06513; 56.04948; 68.01309; 82.06513 |
| 14 | N-Desethylvardenafil | C21H28N6O4S | 17.10 | M + H | 461.1966 | 169.09715; 344.14791; 110.06004; 299.11387; 316.11661; 123.09167; 68.01309; 82.06513; 56.04948 |
| 15 | Piperazonifil | C25H34N6O4 | 17.10 | M + H | 483.2726 | 465.26167; 436.22269; 429.52412; 408.22737; 380.20885; 339.1819; 297.13488; 266.45598; 244.12189; 203.11833; 153.1027; 127.08668; 99.0923; 72.08144 |
| 16 | Vardenafil | C23H32N6O4S | 17.20 | M + H | 489.2279 | 169.09715; 344.14791; 110.06004; 299.11387; 72.08078; 123.09167; 70.06513; 376.1074; 68.01309; 113.10732 |
| 17 | Avanafil | C23H26ClN7O3 | 17.33 | M + H | 484.1858 | 155.02582; 375.12184; 105.03349; 77.03858; 95.04914; 53.03858; 357.11128; 233.1033; 67.05423; 221.1033 |
| 18 | Isosildenafil | C22H30N6O4S | 17.35 | M + H | 475.2122 | 58.06513; 99.09167; 283.11895; 100.0995; 56.04948; 253.072; 70.06513; 311.15025; 225.07709 |
| 19 | Hydroxyhomosildenafil | C23H32N6O5S | 17.36 | M + H | 505.2228 | 99.09167; 70.06513; 58.06513; 84.0682; 97.07602; 283.11895; 88.07569; 129.10224; 112.0995; 311.15025 |
| 20 | N-Desmethylsildenafil | C21H28N6O4S | 17.37 | M + H | 461.1966 | 85.07602; 283.11895; 311.15025; 56.04948; 299.10868; 225.07709; 254.07983; 253.072; 377.1278; 344.14791 |
| 21 | Sildenafil | C22H30N6O4S | 17.39 | M + H | 475.2122 | 58.06513; 100.0995; 99.09167; 56.04948; 283.11895; 70.06513; 311.15025; 225.07709; 299.11387 |
| 22 | Homosildenafil | C23H32N6O4S | 17.47 | M + H | 489.2279 | 72.08078; 58.06513; 99.09167; 113.10732; 70.06513; 283.11895; 84.08078; 71.07295; 114.11515; 311.15025 |
| 23 | Acetaminotadalafil | C23H20N4O5 | 17.60 | M + H | 433.1507 | 204.08078; 262.08626; 135.04406; 205.0886; 233.08352; 232.07569; 169.07602; 191.07295; 263.09408; 250.08626 |
| 24 | Aminotadalafil | C21H18N4O4 | 17.60 | M + H | 391.1401 | 204.08078; 135.04406; 262.08626; 233.08352; 169.07602; 232.07569; 250.08626; 191.07295; 203.07295 |
| 25 | Sildenafil N-oxide | C22H30N6O5S | 17.60 | M + H | 491.2071 | 99.09167; 56.04948; 70.06513; 404.1387; 344.14791; 58.06513; 97.07602; 283.11895; 311.15025; 377.1278 |
| 26 | Cyclopentylnafil | C26H36N6O4S | 17.70 | M + H | 529.2592 | 461.19682; 377.13029; 344.1461; 313.16608; 277.28223; 237.59493; 210.18739; 169.09731; 142.733; 98.09704; 75.59057 |
| 27 | Dimethylsildenafil | C23H32N6O4S | 17.71 | M + H | 489.2279 | 99.09167; 71.07295; 56.04948; 113.10732; 70.06513; 283.11895; 311.15025; 84.08078; 377.1278; 225.07709 |
| 28 | Nortadalafil | C21H17N3O4 | 17.77 | M + H | 376.1292 | 204.08078; 262.08626; 135.04406; 233.08352; 232.07569; 169.07602; 191.07295; 254.0924; 250.08626 |
| 29 | Udenafil | C25H36N6O4S | 17.98 | M + H | 517.2592 | 84.08078; 112.11208; 283.11895; 58.06513; 325.1659; 299.11387; 81.06988; 255.12404; 79.05423; 82.06513 |
| 30 | Benzamidenafil | C19H23N3O6 | 18.02 | M + H | 390.166 | 151.07536; 107.04914; 135.04406; 91.05423; 79.05423; 105.03349; 90.0464; 136.05188; 65.03858; 93.03349 |
| 31 | Norneovardenafil | C18H20N4O4 | 18.07 | M + H | 357.1557 | 169.07602; 110.06004; 329.12443; 328.11661; 123.09167; 68.01309; 300.08531; 55.05423; 82.06513; 95.06037 |
| 32 | Propoxyphenyl-homohydroxysildenafil | C24H34N6O5S | 18.13 | M + H | 519.2384 | 99.09167; 70.06513; 283.11895; 84.0682; 97.07602; 299.11387; 129.10224; 88.07569; 112.0995; 255.12404 |
| 33 | O-desethyl-o-propyl sildenafil | C23H32N6O4S | 18.14 | M + H | 489.2285 | 447.1196; 416.97849; 391.14451; 347.08125; 325.16612; 283.11909; 252.20022; 230.78935; 193.95794; 163.05384; 107.28071; 100.10004; 91.75806; 70.06595; 58.06599 |
| 34 | 2-Hydroxypropyl nortadalafil | C24H23N3O5 | 18.20 | M + H | 434.1711 | 135.04406; 169.07602; 204.08078; 262.08626; 284.13935; 197.07094; 130.06513; 115.05423; 232.07569; 312.13427 |
| 35 | Propoxyphenyl aildenafil | C24H34N6O4S | 18.39 | M + H | 503.2447 | 461.19514; 391.14362; 347.08197; 325.16609; 283.11925; 256.09442; 189.66799; 159.62481; 137.61562; 113.1077; 99.09223; 91.76256; 71.07376 |
| 36 | Acetil acid | C18H20N4O4 | 18.45 | M + H | 357.1557 | 285.1345; 300.08487; 313.16528; 273.23201; 234.78161; 329.12441; 57.55269; 76.77712; 91.7671; 128.3394; 166.09776 |
| 37 | Tadalafil | C22H19N3O4 | 18.69 | M + H | 390.1448 | 204.08078; 135.04406; 262.08626; 169.07602; 205.0886; 232.07569; 233.08352; 240.11314; 268.10805; 250.08626 |
| 38 | Depiperazino-thiosildenafil | C17H20N4O4S2 | 18.80 | M + H | 409.1012 | 381.06896; 365.03707; 352.03045; 328.13556; 300.10448; 272.07283; 253.43238; 218.38203; 200.90222; 182.07341; 146.98571; 130.30821; 91.75983; 69.50264 |
| 39 | Mutaprodenafil | C27H35N9O5S2 | 18.95 | M + H | 630.2282 | 142.00711; 602.23247; 560.22363; 516.1504; 489.22772; 439.15549; 404.13937; 377.12856; 344.14797; 312.15851; 288.21153; 219.20777; 163.22714; 113.10774; 84.98616 |
| 40 | Gendenafil | C19H22N4O3 | 19.24 | M + H | 355.1765 | 327.14517; 285.1346; 298.10604; 256.09548; 311.11387; 69.04472; 120.04439; 154.0611; 313.1659; 166.09749 |
| 41 | Hydroxychlorodenafil | C19H23ClN4O3 | 19.26 | M + H | 391.1531 | 313.12952; 285.1346; 363.12184; 256.09548; 120.04439; 69.04472; 166.09883; 78.99452; 327.14517; 255.08765 |
| 42 | Hydroxythiovardenafil | C23H32N6O4S2 | 19.57 | M + H | 521.1999 | 167.06375; 360.12506; 99.09167; 315.09037; 138.02462; 150.10257; 58.06513; 299.09611; 70.06513; 332.09307 |
| 43 | Chloropretadalafil | C22H19ClN2O5 | 19.65 | M + H | 427.1055 | 135.04406; 274.08559; 204.08078; 216.08078; 189.06988; 262.08674; 244.0735; 302.08117 |
| 44 | Chlorodenafil | C19H21ClN4O3 | 19.79 | M + H | 389.1375 | 361.10619; 285.1346; 311.11387; 154.0611; 166.09749; 69.0573; 256.09548; 76.97887; 165.0183 |
| 45 | Benzylsildenafil | C28H34N6O4S | 20.01 | M + H | 551.2435 | 91.05423; 65.03858; 134.09643; 377.1278 |
| 46 | Nitrodenafil | C17H19N5O4 | 20.09 | M + H | 358.151 | 330.11968; 316.11661; 154.0611; 256.09548; 68.0369; 255.08765; 313.11694; 227.09274; 269.1033; 136.05054 |
| 47 | Pseudovardenafil | C22H29N5O4S | 20.21 | M + H | 460.2013 | 169.09715; 110.06004; 344.14791; 299.11387; 123.09167; 284.12678; 68.01309; 82.06513; 55.05423; 95.06037 |
| 48 | Imidazosagatriazinone | C17H20N4O2 | 20.32 | M + H | 313.1659 | 285.1346; 256.09548; 120.04439; 68.0369; 255.08765; 241.072; 269.1033; 69.04472; 154.0611; 94.02874 |
| 49 | Propoxyphenylthio-hydroxyhomosildenafil | C24H34N6O4S2 | 20.55 | M + H | 535.2156 | 99.09167; 70.06513; 56.04948; 299.09611; 58.06513; 84.0682; 129.10224; 315.09037; 88.07569; 271.10119 |
| 50 | Thiohomosildenafil | C23H32N6O3S2 | 20.55 | M + H | 505.205 | 72.08078; 99.09167; 113.10732; 56.04948; 299.09611; 70.06513; 84.08078; 327.12741; 71.07295; 355.15806 |
| 51 | Hydroxythio-homosildenafil | C23H32N6O4S2 | 20.56 | M + H | 521.1999 | 99.09167; 70.06513; 58.06513; 84.0682; 299.09611; 129.10224; 97.07602; 88.07569; 327.12741; 112.0995 |
| 52 | Norneosildenafil | C22H29N5O4S | 20.64 | M + H | 460.2013 | 283.11895; 84.08078; 299.09611; 311.15025; 154.0611; 316.11661; 255.12404; 344.14791; 166.09749 |
| 53 | Thiosildenafil | C23H32N6O3S2 | 21.47 | M + H | 505.205 | 99.09167; 71.07295; 299.09611; 113.10732; 56.04948; 70.06513; 327.12741; 84.08078; 241.0542; 298.08828 |
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