Journal of Cancer Epidemiology / 2015 / Article / Tab 3

Research Article

Increase in Distant Stage Breast Cancer Incidence Rates in US Women Aged 25–49 Years, 2000–2011: The Stage Migration Hypothesis

Table 3

Three-year relative survival rate (RSR) for women diagnosed at age <50 years with invasive breast cancer in SEER registries for selected years of diagnosis by summary stage at diagnosisa.

Years Distant stage Regional stage Localized stage
NumberbRSR (CL)NumberbRSR (CL)NumberbRSR (CL)

Age 25–39 years
2000-0122730.2 (24.0, 36.4)263480.8 (79.2, 82.4)250995.1 (94.1, 96.1)
2007-0833545.4 (39.6, 51.2)*241887.2 (85.8, 88.6)*235595.7 (94.7, 96.7)

Age 40–49 years
2000-0162232.7 (28.9, 36.5)682086.8 (86.0, 87.6)911197.3 (96.9, 97.7)
2007-0874741.0 (37.2, 44.8)*673790.2 (89.4, 91.0)*998097.8 (97.4, 98.2)

Major ER/PR subgroups, age 25–49 years
ER positive/PR positivec
2000-0128750.1 (44.1, 56.1)460293.2 (92.4, 94.0)570298.9 (98.5, 99.3)
2007-0849956.6 (51.8, 61.4)563595.8 (95.2, 96.4)*786499.2 (98.8, 99.6)
ER negative/PR negativec
2000-0121415.3 (10.3, 20.3)220869.7 (67.7, 71.7)250792.2 (90.0, 93.4)
2007-0832627.4 (22.2, 32.6)*222375.4 (73.4, 77.4)*262992.9 (91.7, 94.1)

aSEER summary stage 2000 (see text) [3, 7, 8].
bNumber of cases at start of follow-up, after exclusion of those with breast cancer as other than their first or only reportable tumor in the SEER database, and breast cancers ascertained by death certificate or autopsy only (see text). With follow-up through December 2011 [7], all cases diagnosed in 2007-08 had the potential to survive at least 3 years after diagnosis (see text).
cEstrogen receptor (ER)/progesterone receptor (PR) (see Table 2 and text). Other ER/PR categories involved small numbers (see text).
CL: confidence limits, lower and upper (95%).
SEER: Surveillance, Epidemiology, and End Results Program of the National Cancer Institute.
*CL for RSR for this period do not overlap with CL for 2000-01.