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Journal of Chemistry
Volume 2016 (2016), Article ID 8768130, 5 pages
Research Article

Ultrasound-Assisted Extraction of Total Flavonoids from Corn Silk and Their Antioxidant Activity

1Department of Pharmacy, The First Affiliated Hospital of Chengdu Medical College, Chengdu 610500, China
2Department of Chinese Traditional Herbal, Agronomy College, Sichuan Agriculture University, Chengdu 611130, China

Received 14 September 2015; Accepted 29 December 2015

Academic Editor: Alberto Ritieni

Copyright © 2016 Ling-Li Zheng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Object. Ultrasound-assisted extraction of total flavonoids from corn silk and their antioxidant activities were studied. Methods. Response surface methodology was adopted to optimize the extraction conditions and antioxidant activities of the extracted total flavonoids were detected through ferric reducing antioxidant power (FRAP) assay. Results. Through a three-level, three-variable Box-Behnken design of response surface methodology (RSM) adopting yield as response, the optimal conditions were determined as follows: ultrasonic power 500 W, extraction time 20 min, material solvent ratio 1 : 20, and ethanol concentration 30%. Under the optimum conditions, the extraction yield of total flavonoids was 1.13%. FRAP value of total flavonoids extracted from corn silk was 467.59 μmol/L. Conclusion. The total flavonoids of corn silk could be developed as food natural antioxidant reagents.