Research Article

Purification of Crocin-I from Gardenia Yellow by Macroporous Resin Columns In-Series and Its Antidepressant-Like Effect

Table 4

Effects of crocin-I (20, 40, and 70 mg/kg, i.g.) and Gardenia yellow (30, 70, and 120 mg/kg, i.g.) on the weight, AST, and ALT of mice ().

GroupASTALT△weight

Control76.70 ± 22.5827.30 ± 14.801.41 ± 0.65
Fluoxetine(20 mg/kg)78.90 ± 19.8926.10 ± 4.310.70 ± 0.97
Crocin-I(20 mg/kg)76.10 ± 32.3226.80 ± 6.031.35 ± 0.63
(40 mg/kg)72.00 ± 12.7021.10 ± 6.452.20 ± 0.46
(70 mg/kg)82.22 ± 12.8729.20 ± 12.691.51 ± 0.51

Gardenia yellow(30 mg/kg)84.64 ± 21.3733.55 ± 31.981.41 ± 0.50
(70 mg/kg)70.09 ± 8.4625.45 ± 5.791.81 ± 0.86
(120 mg/kg)76.73 ± 17.4631.00 ± 15.311.81 ± 0.57

Note: data were expressed as mean ± SD. and ∗∗ vs control.