Research Article
Purification of Crocin-I from Gardenia Yellow by Macroporous Resin Columns In-Series and Its Antidepressant-Like Effect
Table 4
Effects of crocin-I (20, 40, and 70 mg/kg, i.g.) and
Gardenia yellow (30, 70, and 120 mg/kg, i.g.) on the weight, AST, and ALT of mice (
).
| Group | AST | ALT | △weight |
| Control | | 76.70 ± 22.58 | 27.30 ± 14.80 | 1.41 ± 0.65 | Fluoxetine | (20 mg/kg) | 78.90 ± 19.89 | 26.10 ± 4.31 | 0.70 ± 0.97 | Crocin-I | (20 mg/kg) | 76.10 ± 32.32 | 26.80 ± 6.03 | 1.35 ± 0.63 | (40 mg/kg) | 72.00 ± 12.70 | 21.10 ± 6.45 | 2.20 ± 0.46 | (70 mg/kg) | 82.22 ± 12.87 | 29.20 ± 12.69 | 1.51 ± 0.51 |
| Gardenia yellow | (30 mg/kg) | 84.64 ± 21.37 | 33.55 ± 31.98 | 1.41 ± 0.50 | (70 mg/kg) | 70.09 ± 8.46 | 25.45 ± 5.79 | 1.81 ± 0.86 | (120 mg/kg) | 76.73 ± 17.46 | 31.00 ± 15.31 | 1.81 ± 0.57 |
|
|
Note: data were expressed as mean ± SD. and ∗∗ vs control. |