Review Article

Neural Degeneration in the Retina of the Streptozotocin-Induced Type 1 Diabetes Model

Figure 2

Oxidative stress in the retina of the STZ-induced diabetes model mouse. Dihydroethidium (DHE) indicates ROS in the retina (a). The level of diabetes-induced ROS in the retina is decreased by constant lutein treatment. Fluorescence intensity in the INL relative to that of nondiabetic mice was measured by the Image J program (b). DHE, dihydroethidium; ROS, reactive oxygen species; GCL, ganglion cell layer; IPL, inner plexiform layer; INL, inner nuclear layer (original copyright; [8], Figure 1, reproduced with the kind permission of Springer Science + Business Media.)
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