Journal of Diabetes Research / 2012 / Article / Tab 3

Clinical Study

Stepwise Increases in Left Ventricular Mass Index and Decreases in Left Ventricular Ejection Fraction Correspond with the Stages of Chronic Kidney Disease in Diabetes Patients

Table 3

Determinants of left ventricular ejection fraction (LVEF) in study patients.

CharacteristicsUnivariateMultivariate (forward)
Standardized coefficient PStandardized coefficient P

Age (year)0.0620.297
Male versus female−0.223<0.001−0.227<0.001
Smoking(ever versus never)−0.0900.130
Coronary artery disease−0.1690.004−0.1530.008
Cerebrovascular disease−0.0710.235
Congestive heart failure−0.1550.009
CKD stage−0.1510.011−0.1730.007
Systolic blood pressure (mmHg)−0.0380.528
Diastolic blood pressure (mmHg)−0.0920.130
Pulse pressure (mmHg)0.0200.747
Body mass index (kg/m2)0.0100.871

Laboratory parameters
 Albumin (g/L)0.258< 0.0010.1880.003
 Fasting glucose (mmol/L)−0.0970.107
  HbA1c (%)−0.0400.509
 Triglyceride (Log mmol/L)−0.0390.518
 Cholesterol (mmol/L)−0.0690.247
 Hemoglobin (g/L)0.1030.083
 Calcium (mmol/L)0.1220.044
  Phosphate (mmol/L)−0.1680.005
 Calcium-phosphorous product (mmol2/L2)−0.1030.088
 Uric acid (μmol/L)−0.1460.015
Proteinuria−0.0960.106

Medications
 Aspirin use (%)−0.1320.028
 ACEI and/or ARB use (%)0.2030.0010.1430.014
 Non-ACEI and/or ARB antihypertensive drug use (%)0.0480.422
 Statin use (%)0.0040.951

Values expressed as standardized coefficient . Abbreviations are the same as Table 1.