Insulin Sensitivity and Beta-Cell Function Are Associated with Arterial Stiffness in Individuals without Hypertension
Table 3
Independent association of brachial-ankle pulse wave velocity with indices of insulin resistance, insulin sensitivity, and beta-cell function.
Normotensive
Hypertensive
Beta
Adjusted
Beta
Adjusted
Model 1, age, gender adjusted
InHOMA-IR
0.508
<0.001
0.261
0.403
0.120
0.198
QUICKI
0.532
<0.001
0.383
0.153
Matsuda
−0.226
<0.001
−0.086
0.195
HOMA-β
−0.131
<0.001
−0.069
0.141
Model 2, model 1 + BMI, WHR, HR, and MAP
InHOMA-IR
0.257
0.043
0.378
0.369
0.125
0.337
QUICKI
0.223
0.023
0.456
0.067
Matsuda
−0.131
<0.001
−0.143
0.023
HOMA-β
−0.088
<0.001
−0.009
0.839
Model 3, model 2 + LIPIDS
InHOMA-IR
0.196
0.076
0.380
0.339
0.160
0.341
QUICKI
0.226
0.046
0.430
0.084
Matsuda
−0.114
<0.001
−0.126
0.046
HOMA-β
−0.082
<0.001
−0.005
0.903
HOMA-IR: homeostasis model assessment of insulin resistance, QUICKI: Quantitative Insulin Sensitivity Check Index. HOMA-IR was log-transformed for comparison.
