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Journal of Diabetes Research
Volume 2013 (2013), Article ID 175901, 8 pages
http://dx.doi.org/10.1155/2013/175901
Research Article

Effects of Long-Term Treatment with Ranirestat, a Potent Aldose Reductase Inhibitor, on Diabetic Cataract and Neuropathy in Spontaneously Diabetic Torii Rats

Ayumi Ota,1 Akihiro Kakehashi,1 Fumihiko Toyoda,1 Nozomi Kinoshita,1 Machiko Shinmura,1 Hiroko Takano,1 Hiroto Obata,1 Takafumi Matsumoto,2 Junichi Tsuji,2 Yoh Dobashi,3 Wilfred Y. Fujimoto,3,4 Masanobu Kawakami,3 and Yasunori Kanazawa3

1Department of Ophthalmology, Jichi Medical University, Saitama Medical Center, 1-847 Amanuma-cho, Omiya-ku, Saitama-shi 330-8503, Japan
2Pharmacology Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd., Osaka 554-0022, Japan
3Department of Integrated Medicine I, Jichi Medical University, Saitama Medical Center, Saitama 330-8503, Japan
4Division of Metabolism, Endocrinology and Nutrition, University of Washington School of Medicine, Seattle, WA, USA

Received 22 December 2012; Accepted 29 January 2013

Academic Editor: Tomohiko Sasase

Copyright © 2013 Ayumi Ota et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Ayumi Ota, Akihiro Kakehashi, Fumihiko Toyoda, et al., “Effects of Long-Term Treatment with Ranirestat, a Potent Aldose Reductase Inhibitor, on Diabetic Cataract and Neuropathy in Spontaneously Diabetic Torii Rats,” Journal of Diabetes Research, vol. 2013, Article ID 175901, 8 pages, 2013. doi:10.1155/2013/175901