Ethyl Pyruvate Inhibits Retinal Pathogenic Neovascularization by Downregulating HMGB1 Expression
Figure 4
The effect of EP on retinal of HMGB1 expression in OIR mice. (a) Representative photomicrographs of retinal sections labeled with an anti-HMGB1 antibody. Retinas from control (Con), OIR (OIR), 50 mg/kg EP-treated (EP-50), and 100 mg/kg EP-treated (EP-100) mice. (b) Morphological quantitative analyses of nuclei (c) and cytoplasm (d) HMGB1-positive signal intensity. The data are expressed as the mean ± SE . versus the Con group.
