Increased Oxidation as an Additional Mechanism Underlying Reduced Clot Permeability and Impaired Fibrinolysis in Type 2 Diabetes

Table 3

Univariate correlations of clot permeability (, 10⁻⁹ cm²) and clot lysis time (CLT, min).

		,	CLT		CLT^1
HbA1c, %		−0.30	0.14
		0.0002	0.10
DM duration		−0.32	0.14
		0.0001	0.09
Nitrotyrosine, nM/mL		−0.44	0.19	−0.47	0.14
		<0.001	0.02	<0.001	0.08
AGE, U/mL		−0.20	0.107	−0.17	−0.02
		0.01	0.20	0.05	0.82
sRAGE, ng/mL		−0.27	0.13	−0.26	0.05
		0.001	0.11	0.001	0.53
, pg/mL		−0.22	0.13	−0.25	0.11
		0.007	0.10	0.003	0.19
oxLDL, ng/mL		−0.33	0.48	−0.21	0.41
		0.0001	<0.0001	0.01	<0.0001
Glucose, mmol/L		−0.14	0.20
		0.07	0.02

after adjustment for fibrinogen, DM duration time, and HbA1c.
Abbreviations: see Tables 1 and 2.