Research Article

Diabetes Complications at Presentation and One Year by Glycated Haemoglobin at Diagnosis in a Multiethnic and Diverse Socioeconomic Population: Results from the South London Diabetes Study

Table 3

Prospective comparisons between participants diagnosed with HbA1c < 48 mmol/mol and those diagnosed with HbA1c ≥ 48 mmol/mol at year 1.

with dataHbA1c < 48 mmol/mol (6.5%)HbA1c ≥ 48 mmol/mol (6.5%) value

Median (IQR) HbA1c at year 1
HbA1c (mmol/mol)125143.17 (40.98–47.54),49.72 (45.35–57.37)<0.0001
HbA1c (%)6.10 (5.90–6.50)6.70 (6.30–7.40),

New complication status at year 1
Retinopathy (%)122032 (10.88)126 (13.61)0.2257
Microalbuminuria (%)102522 (9.21)123 (15.65)0.0123
MI (%)127810 (3.38)12 (1.22)0.0124
Stroke (%)12724 (1.4)7 (0.72)0.2951

Cumulative microalbuminuria and MI status at year 1
Microalbuminuria (%)121839 (14.77)191 (20.02)0.0540
MI (%)148729 (8.55)59 (5.14)0.0190

Medication status at year 1
Receiving oral agents (%)129692 (30.6)715 (71.9)<0.0001
Receiving insulin (%)12948 (2.67)37 (3.72)0.3817

Cardiovascular risk factor status (SD) at year 1
BMI (kg/m2)130831.28 (±6.44)32.14 (±6.35)0.0400
BPD (mmHg)128280.21 (±10.76)82.22 (±10.91)0.0057
BPS (mmHg)1284135.42 (±18.28)134.57 (±17.23)0.4614
LDL-C (mmol/L)11642.49 (±0.80)2.51 (±0.84)0.7485
HDL-C (mmol/L)12001.32 (±0.48)1.25 (±0.34)0.0081
Total cholesterol (mmol/L)12344.40 (±1.30)4.40 (±1.20)0.0942
Triglycerides (mmol/L)11642.49 (±0.80)2.51 (±0.84)0.5454
Smoking status (%)1149190 (21.62)41 (15.19)0.0211