Journal of Diabetes Research

Animal Models of Diabetes and its Associated Complications


Publishing date
24 May 2013
Status
Published
Submission deadline
04 Jan 2013

1Department of Biochemistry, School of Life Sciences, University of KwaZulu-Natal (Westville Campus), Durban 4000, South Africa

2Department of Endocrinology and Metabolism, Kanazawa Medical University, Kahoku-gun, Ishikawa 920-0293, Japan

3Laboratory of Developmental Physiology, University of Paris, Paris, France


Animal Models of Diabetes and its Associated Complications

Description

Diabetes is a major threat to global public health. According to the latest data from the International Diabetes Federation (IDF), at least 366 million people are living with diabetes and this number is projected to be 552 million by 2030. At least 50% of the people with diabetes have suffered from one or two major diabetic complications such as diabetic cardiomyopathy, nephropathy, neuropathy, retinopathy, and diabetic foot diseases. Development of an authentic model for each type of diabetes and its associated complications, which exactly mimics the human pathogenesis, is very crucial not only for a better understanding of the core causes of the diseases but also for the development and routine pharmacological screening of novel antidiabetic drugs. A number of genetic and nongenetic animal models of the different types of diabetes and their associated complications have been developed in the last three decades but none of them are without limitations.

We invite investigators to contribute original research and review articles in the area of the development of a better and more authentic animal model of the different types of diabetes and their associated complications, which may be more suitable to understand the major causes of the disease and its complications and may be easier to induce, widely available, cost effective as well as will be suitable for the development and routine pharmacological screening of antidiabetic drugs, functional and medicinal foods, and natural products. Potential topics include, but are not limited to:

  • Genetic or spontaneously induced animal models of type 1 or type 2 diabetes
  • Nongenetic or experimentally induced animal models of type 1 or type 2 diabetes
  • Animal models of gestational diabetes
  • Animal models of diabetic complications such as:
    • Diabetic cardiomyopathy
    • Diabetic retinopathy
    • Diabetic nephropathy
    • Diabetic retinopathy and
    • Diabetic foot diseases

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jdr/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/jdr/amd/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2013
  • - Article ID 593204
  • - Editorial

Animal Models of Diabetes and Its Associated Complications

Md. Shahidul Islam | Daisuke Koya | Bernard Portha
  • Special Issue
  • - Volume 2013
  • - Article ID 106594
  • - Review Article

Animal Models of Diabetic Retinopathy: Summary and Comparison

Angela Ka Wai Lai | Amy C. Y. Lo
  • Special Issue
  • - Volume 2013
  • - Article ID 162846
  • - Review Article

Novel Role of Parathyroid Hormone-Related Protein in the Pathophysiology of the Diabetic Kidney: Evidence from Experimental and Human Diabetic Nephropathy

Montserrat Romero | Arantxa Ortega | ... | Ricardo J. Bosch
  • Special Issue
  • - Volume 2013
  • - Article ID 254529
  • - Research Article

Outcome of Acute Renal Injury in Diabetic Mice with Experimental Endotoxemia: Role of Hypoxia-Inducible Factor-1α

A. Ortega | A. Fernández | ... | R. J. Bosch
  • Special Issue
  • - Volume 2013
  • - Article ID 149452
  • - Review Article

Animal Models of Diabetic Neuropathy: Progress Since 1960s

Md. Shahidul Islam
  • Special Issue
  • - Volume 2013
  • - Article ID 342479
  • - Research Article

IL-10 Induction from Implants Delivering Pancreatic Islets and Hyaluronan

Paul L. Bollyky | Robert B. Vernon | ... | John A. Gebe
  • Special Issue
  • - Volume 2013
  • - Article ID 134395
  • - Research Article

The Role of Adrenomedullin in the Renal NADPH Oxidase and (Pro)renin in Diabetic Mice

Michio Hayashi | Akihiro Tojo | ... | Toshiro Fujita
  • Special Issue
  • - Volume 2013
  • - Article ID 463740
  • - Research Article

Both ERK/MAPK and TGF-Beta/Smad Signaling Pathways Play a Role in the Kidney Fibrosis of Diabetic Mice Accelerated by Blood Glucose Fluctuation

Xiaoyun Cheng | Wenke Gao | ... | Xiyun Ye
  • Special Issue
  • - Volume 2013
  • - Article ID 473575
  • - Review Article

Mild Diabetes Models and Their Maternal-Fetal Repercussions

D. C. Damasceno | Y. K. Sinzato | ... | M. V. C. Rudge
  • Special Issue
  • - Volume 2013
  • - Article ID 716219
  • - Research Article

Antioxidant N-Acetylcysteine Attenuates the Reduction of Brg1 Protein Expression in the Myocardium of Type 1 Diabetic Rats

Jinjin Xu | Shaoqing Lei | ... | Zhengyuan Xia
Journal of Diabetes Research
 Journal metrics
Acceptance rate34%
Submission to final decision85 days
Acceptance to publication27 days
CiteScore3.020
Impact Factor3.040
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