Review Article

Understanding the Antinutritional Factors and Bioactive Compounds of Kodo Millet (Paspalum scrobiculatum) and Little Millet (Panicum sumatrense)

Table 5

Bioactive compounds found in kodo/little millets.

Bioactive compounds
CompoundsIUPAC nameChemical formulaHealth benefitsKodo/LittleReferences

Catechin(2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2h-chromene-3,5,7-triolC15H14O6Anticancer, anti-obesity, and helps in treatment for Alzheimer’s and Parkinson’s diseaseKodoKhan et al. [56]; shankar et al. [57]; singh et al. [58]

Naringin7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-oneC27H32O14Anti-apoptotic, anticarcinogenic, anti-inflammatory, antiulcer, anti-osteoporoticKodoWang et al. [59]

p-Coumaric acid(2E)-3-(4-hydroxyphenyl)prop-2-enoic acidC9H8O3Anti-inflammatory, anticancer, anti-obesity, reduces lipid peroxidation, cholesterol oxidation, and LDPKodoBoz, [60]; Kannan et al. [61]; Ferguson et al. [62]

Taxifolin(2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-2,3-dihydrochromen-4-oneC15H14O6Anti-inflammatoryKodoGupta et al. [63]

Ferulic acid(2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acidC10H10O4Antithrombotic, anti-allergic, antimicrobial, anti-inflammatory, antiviral, anticarcinogenic, hepta-protective, vasodilatory effectKodoGraf, [64]; Akihisa et al. [65]; Oosterveld et al. [66]; Rukkumani et al. [67]

Sinapic acid3,5-Dimethoxy-4-hydroxycinnamic acidC11H12O5Anticarcinogenic and anti-inflammatoryKodoConnelly et al. [68]

Pterin-6-carboxylic acid2-Amino-4-oxo-3h-pteridine-6-carboxylic acidC7H5N5O3AntitumorKodoHadi et al. [69]

Campesterol(3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5,6-dimethylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-olC28H48OLowers cholesterol, shows anticarcinogenic and chemopreventive effectKodoChoi et al. [70]

Kaempferol3,4′,5,7-TetrahydroxyflavoneC15H10O6Lowers the risk of chronic diseasesLittlePradeep & Sreerama, [71]

Luteolin2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-oneC15H10O6Antioxidant, anti-inflammatoryLittlePradeep & Sreerama, [25]; Dykes & Rooney, [72]

Apigenin5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-oneC15H10O5Antidiabetic, antirheumatic, anticancerousLittleThakur & Tiwari, [73]