Evaluation of Natural Peptides to Prevent and Reduce the Novel SARS-CoV-2 Infection

Table 2

Inhibitory effects of peptides on the interaction between SARS-CoV-2 spike glycoprotein and the human ACE2 receptor and on the ACE2 activity. a = 15 g/L, b = 7.5 g/L, c = 15 g/L (1 : 1), and d = 15 g/L (2 : 1), n.d. = not detected.

Peptides	Spike-ACE2			ACE2
	PI (%)^a	PI (%)^c	PI (%)^d	PI (%)^a	PI (%)^b
LSDRFS	79.56	—	—	95.50	52.17
SDRFSY	84.65	—	—	95.81	71.33
VIKP	62.03	—	—	94.37	16.4
GGV	34.99	—	—	6.07	n.d
LSDRFS + GGV	—	4.08	38.29	—	—