Evaluation of Modified Date Palm (Phoenix dactylifera L.) Mucilage as a Potential Pharmaceutical Excipient

Table 2

Effect of temperature on solubility and swelling index of HPMC, paracetamol, and date palm mucilage granules.

Sr. No.

Property

T (°C)

Crude mucilage

Purified mucilage

Acidic hydrolyzed mucilage

Basic hydrolyzed mucilage

Amylase hydrolyzed mucilage

Cellulase hydrolyzed mucilage

Poly acrylamide grafted mucilage

ZnO-NPs mucilage

CuO-NPs mucilage

Ag-NPs mucilage

Au-NPs mucilage

HPMC

Paracetamol

1

Solubility (%)

25

5.2 ± 0.019

5.92 ± 0.024

4.7 ± 0.03

5.5 ± 0.01

6.1 ± 0.01

6.5 ± 0.02

4.3 ± 0.1

0.07 ± 0.003

0.5 ± 0.001

0.045 ± 0.001

0.03 ± 0.0019

9.6 ± 0.09

12.5 ± 0.13

35

5.8 ± 0.02

6.8 ± 0.031

5.1 ± 0.01

5.9 ± 0.13

6.3 ± 0.08

6.9 ± 0.02

4.4 ± 0.08

0.1 ± 0.005

0.55 ± 0.003

0.051 ± 0.001

0.033 ± 0.001

11.5 ± 0.1

13.1 ± 0.11

50

7.4 ± 0.015

8.2 ± 0.11

5.7 ± 0.01

6.1 ± 0.014

7.1 ± 0.02

7.4 ± 0.1

4.9 ± 0.12

0.12 ± 0.001

0..59 ± 0.001

0.071 ± 0.003

0.041 ± 0.002

15.3 ± 0.13

13.9 ± 0.1

65

7.9 ± 0.05

9.1 ± 0.01

6.4 ± 0.013

6.5 ± 0.011

7.5 ± 0.14

7.7 ± 0.09

5.6 ± 0.016

0.18 ± 0.001

0.65 ± 0.002

0.085 ± 0.001

0.055 ± 0.001

15.8 ± 0.11

14.4 ± 0.1

80

8.8 ± 0.05

11.3 ± 0.05

7.6 ± 0.06

9.5 ± 0.1

8.5 ± 0.11

8.2 ± 0.05

6.2 ± 0.06

0.26 ± 0.008

0.85 ± 0.001

0.15 ± 0.009

0.063 ± 0.0013

17.3 ± 0.1

16.9 ± 0.08

2

Swelling index

25

1.9 ± 0.022

1.99 ± 0.037

1.65 ± 0.04

1.85 ± 0.016

2.13 ± 0.01

2.2 ± 0.68

1.68 ± 0.13

0.58 ± 0.008

0.51 ± 0.006

0.43 ± 0.001

0.31 ± 0.003

3.9 ± 0.15

4.45 ± 0.17

35

1.9 ± 0.017

2.3 ± 0.042

1.96 ± 0.09

2.11 ± 0.019

2.45 ± 0.05

2.7 ± 0.59

1.77 ± 0.07

0.67 ± 0.002

0.54 ± 0.001

0.49 ± 0.004

0.35 ± 0.002

4.5 ± 0.28

5.74 ± 0.14

50

2.1 ± 0.009

2.5 ± 0.018

2.01 ± 0.18

2.15 ± 0.008

2.73 ± 0.05

2.8 ± 0.41

1.81 ± 0.18

0.7 ± 0.009

0.58 ± 0.009

0.53 ± 0.004

0.4 ± 0.002

6.6 ± 0.36

6.16 ± 0.09

65

2.5 ± 0.011

2.7 ± 0.032

2.06 ± 0.18

2.22 ± 0.01

3.31 ± 0.08

3.2 ± 0.44

2.02 ± 0.14

0.76 ± 0.005

0.62 ± 0.001

0.58 ± 0.002

0.41 ± 0.001

11.39 ± 0.95

6.58 ± 0.17

80

2.6 ± 0.025

3.3 ± 0.013

2.19 ± 0.02

2.32 ± 0.04

3.55 ± 0.16

3.4 ± 0.75

2.12 ± 0.19

0.82 ± 0.002

0.65 ± 0.007

0.61 ± 0.01

0.48 ± 0.0018

29.54 ± 1.29

6.75 ± 0.11