Aflatoxin M1 Contamination of Ghanaian Traditional Soft Cottage Cheese (Wagashie) and Health Risks Associated with Its Consumption
Table 7
Risk evaluation for AFM1 via consumption of wagashie.
Region
Av. body wgt. (kg)
EDI (ng/kg bw/day)
MOE
Cancer risk (cases/100,000 person/yr)
Northern
Infants (0–11 mths)
2.9
1.50
0.13
0.048
Toddlers (12–35 mths)
9.8
0.89
0.22
0.029
Children (36 mths-10 yrs)
26
0.34
0.59
0.010
Adolescents (11–17 yrs
46.3
0.19
1.05
6.14 × 10−3
Adults (18–64 yrs)
60.7
0.14
1.43
4.52 × 10−3
Eastern
Infants (0–11 mths)
2.9
1.14
0.18
0.04
Toddlers (12–35 mths)
9.8
0.67
0.30
0.02
Children (36 mths-10 yrs)
26
0.25
0.53
8.08 × 10−3
Adolescents (11–17 yrs)
46.3
0.14
1.43
4.52 × 10−3
Adults (18–64 yrs)
60.7
0.11
1.81
3.55 × 10−3
Margin of exposure-MOE. Means of aflatoxins M1- NR-0.636 µg/kg, ER- 0.482 µg/kg. Daily intake of wagshie for infants was halved (0.5 × 0.0137 kg). Average potency of aflatoxin = 0.0323. Average body weights were obtained from the different ranges referenced by the authors. 1 µg = 1000 ng.