Chemical Profiling and Biological Activities of Ziziphus Mauritiana var. spontanea (Edgew.) R.R. Stewart ex Qaiser & Nazim. and Oenothera Biennis L.

Table 9

Anti-inflammatory activity of Ziziphus mauritiana. var. spontanea.

Treatment	Dose (mg/kg)	Paw volume after drug administration (mean + SEM)
		1 hour	2 hour	3 hour	4 hour	5 hour
Normal saline	10 ml/kg	0.90 ± 0.02	0.77 ± 0.08	0.86 ± 0.10	0.95 ± 0.02	1.50 ± 0.27
Diclofenac sodium	10 mg/kg	0.80 ± 0.04 (11.11%)	0.54 ± 0.04 (29.8%)	0.45 ± 0.03 (47.67%)	0.52 ± 0.04 (45.2%)	0.38 ± 0.08 (75.4%)
Ethyl acetate extract	100 mg/kg	0.86 ± 0.06 (4.44%)	0.68 ± 0.08 (15.58%)	0.75 ± 0.08 (12.7%)	0.65 ± 0.04 (31.57%)	0.53 ± 0.06 (64.6%)
	200 mg/kg	0.88 ± 0.07 (2.22%)	0.57 ± 0.08 (26.0%)	0.66 ± 0.06 (23.2%)	0.55 ± 0.08 (42.1%)	0.47 ± 0.05 (68.6%)
	300 mg/kg	0.76 ± 0.09 (15.5%)	0.59 ± 0.06 (23.3%)	0.64 ± 0.07 (34.3%)	0.53 ± 0.09 (44.2%)	0.45 ± 0.04 (70.0%)
Ethanolic extract	100 mg/kg	0.87 ± 0.03 (3.33%)	0.71 ± 0.04 (7.79%)	0.75 ± 0.18 (12.7%)	0.70 ± 0.14 (26.3%)	0.64 ± 0.19 (57.3%)
	200 mg/kg	0.86 ± 0.12 (4.44%)	0.66 ± 0.10 (23.2%)	0.70 ± 0.24 (26.3%)	0.64 ± 0.12 (57.3%)	0.59 ± 0.04 (60.6%)
	300 mg/kg	0.84 ± 0.09 (6.66%)	0.63 ± 0.09 (18.1%)	0.67 ± 0.12 (22.0%)	0.73 ± 0.10 (23.1%)	0.51 ± 0.10 (66.0%)

Values are expressed as mean ± standard deviation. Significance is shown as significant, more significant, and highly significant.