Prognostic Analysis of Elderly Patients with Multiple Organ Dysfunction Syndrome Undergoing Invasive Mechanical Ventilation
Table 1
General clinical information of the enrolled patients.
Total
28-day survivors (n = 102)
28-day nonsurvivors (n = 249)
Age (years)
77.71 ± 9.22
77.52 ± 9.18
77.86 ± 9.24
0.816
Gender (no., %)
Male
254
72
182 (71.65%)
0.781
Female
97
30
67 (69.07%)
Number of failing organs
3.82 ± 1.22
3.14 ± 1.03
4.09 ± 1.19
<0.001
Vital signs and laboratory tests
Body temperature (°C)
37.81 ± 1.40
37.45 ± 1.25
37.95 ± 1.44
0.021
Heart rate (times/min)
114.7 ± 29.2
104.3 ± 26.1
118.9 ± 29.4
0.001
Breathing rate (times/minute)
24.5 ± 6.7
22.6 ± 5.6
25.3 ± 7.0
0.006
Mean arterial pressure (mmHg)
77.5 ± 22.6
82.1 ± 22.4
75.6 ± 22.5
0.070
Urine output (mL/24 hours)
1671.7 ± 1392.1
1371.8 ± 181.7
1332.1 ± 112.6
<0.001
WBC count (109/L)
12.95 ± 8.20
11.19 ± 5.56
13.66 ± 8.98
0.021
Platelet count (109/L)
126.5 ± 74.7
150.8 ± 69.3
116.7 ± 74.8
0.003
PaO2/FiO2
156.0 ± 85.0
180.7 ± 96.2
142.3 ± 76.2
<0.001
Serum creatinine (μmol/L)
194.2 ± 173.0
141.5 ± 130.0
215.7 ± 183.7
0.002
Serum sodium (mmol/L)
140.05 ± 8.72
137.71 ± 7.01
141.00 ± 9.18
0.016
Serum potassium (mmol/L)
4.22 ± 1.10
3.78 ± 0.80
4.40 ± 1.16
<0.001
Serum albumin (g/L)
30.42 ± 8.72
32.32 ± 10.71
29.65 ± 7.68
0.050
Serum bilirubin (μmol/L)
31.82 ± 61.00
16.43 ± 12.42
38.08 ± 71.05
0.001
Scoring systems
APACHE II
25.6 ± 8.2
18.8 ± 6.1
28.4 ± 7.4
<0.001
APACHE III
96.5 ± 31.4
71.1 ± 24.6
106.9 ± 27.8
<0.001
SAPS II
61.9 ± 17.8
48.1 ± 13.3
67.6 ± 16.3
<0.001
MODS
8.7 ± 3.5
5.9 ± 2.5
9.9 ± 3.2
<0.001
Outcomes of weaning
Success
105
76
29 (27.94%)
<0.001
Failure
169
26
143 (84.62%)
The length of ICU stay (days)
20.93 ± 21.69
17.67 ± 19.99
28.95 ± 23.71
0.001
Quantitative data of normal distribution are presented as mean ± SD. Qualitative data are presented as n. and survivors vs. nonsurvivors. WBC counts: white blood cell counts. APACHE: Acute Physiology and Chronic Health Evaluation. SAPS: sample acute physiological score. MODS: multiple organ dysfunction syndrome. ICU: intensive care unit.
