The Role of the Lactadherin in Promoting Intestinal DCs Development In Vivo and Vitro
Figure 1
The expression of OX62DCs and OX62+CD4+SIRP+DCs of each groups at various development stages (Mean±SD). (a) The expression level of OX62DCs of each group at different stages. (b) The expression level of OX62+CD4+SIRP+ DCs of each group at different stages. (c) Single-cell suspensions of the total PP-DCs in rats were identified by OX62. The difference of OX62DC among groups at different development stages was not significant. (F = 3.0, 0.587, 3.267, and 1.471, resp.; ). Significant growth occurred in LR group for the number of OX62CD4SIRPDCs at age week 3. Levels of OX62CD4SIRP+DC subsets at every age were highly significant in LR group and BR group compared with AR group. Furthermore, the positive cell numbers were higher in LR group than in BR group. The positive cell numbers kept stable in LR group at various ages while the positive cells number increased with age in the other two groups. Significant numbers of OX62CD4SIRPDCs were found in LR and BR group at various ages (Figures 1(b) and 1(c)) compared with AR group (A: BR at W3, B: AR at W3, C: LR at W3, D: BR at W5, E: AR at W5, F: LR at W5, G: BR at W7, H: AR at W7, I: LR at W7, J: BR at W11, K: AR at W11, L: LR at W11). .
