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Clinical and Developmental Immunology
Volume 2012, Article ID 831434, 6 pages
Clinical Study

Systemic Lupus Erythematosus and Systemic Autoimmune Connective Tissue Disorders behind Recurrent Diastolic Heart Failure

Unidad de Alta Resolución Hospitalaría (UARH), Pab. 13, -1, Hospital Marqués de Valdecilla, Avenida Marqués de Valdecilla, 39008 Santander, Spain

Received 12 April 2011; Revised 13 July 2011; Accepted 23 July 2011

Academic Editor: Antonio Fernández-Nebro

Copyright © 2012 Luis Miguel Blasco Mata et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Diastolic heart failure (DHF) remains unexplained in some patients with recurrent admissions after full investigation. A study was directed for screening SLE and systemic autoimmune connective tissue disorders in recurrent unexplained DHF patients admitted at a short-stay and intermediate care unit. It was found that systemic autoimmune conditions explained 11% from all of cases. Therapy also prevented new readmissions. Autoimmunity should be investigated in DHF.