Antibodies to Lactobacilli and Bifidobacteria in Young Children with Different Propensity to Develop Islet Autoimmunity
Table 2
The number of children in different age groups with serum IgG reactivity to different L. rhamnosus GG proteins. The age period when significantly more () antibodies against bacterial proteins were observed compared to the 3-month age group is shown in bold.
L. rhamnosus GG antigenic proteins
3-month
6-month
12-month
24-month
IA-positive
IA-negative
IA-positive
IA-negative
IA-positive
IA-negative
IA-positive
IA-negative
()
()
()
()
()
()
()
()
65 kDa
8 (44)
14 (78)
14 (74)
*
17 (89)
17 (94)
17 (94)
15 (100)
17 (94)
58 kDa
8 (44)
12 (67)
18 (95)
19 (100)
17 (94)
17 (94)
15 (100)
18 (100)
49 kDa
2 (11)
2 (11)
2 (10)
4 (21)
6 (33)
8 (44)
4 (27)
7 (39)
47 kDa
4 (22)
4 (22)
8 (42)
7 (37)
9 (50)
12 (67)
7 (47)
8 (44)
45 kDa
9 (50)
11 (61)
11 (58)
11 (58)
16 (89)
14 (78)
15 (100)
18 (100)
42 kDa
3 (17)
4 (22)
5 (26)
7 (37)
9 (50)
7 (39)
8 (53)
9 (50)
38 kDa
1 (5)
3 (17)
2 (10)
2 (10)
5 (28)
5 (28)
8 (53)
8 (44)
31 kDa
13 (72)
9 (50)
14 (74)
11 (58)
17 (94)
17 (94)
15 (100)
16 (89)
27 kDa
0 (0)
4 (22)
1 (5)
2 (10)
2 (11)
2 (11)
5 (33)
6 (33)
*Number and % (in brackets) of children with positive reactions to this protein.
