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Journal of Immunology Research
Volume 2014, Article ID 762514, 4 pages
http://dx.doi.org/10.1155/2014/762514
Research Article

Association of Helicobacter pylori and iNOS Production by Macrophages and Lymphocytes in the Gastric Mucosa in Chronic Gastritis

FSBI Research Center of Clinical and Experimental Medicine, SB RAMS, Timakova Street 2, Novosibirsk 630117, Russia

Received 17 July 2014; Revised 1 September 2014; Accepted 2 September 2014; Published 18 September 2014

Academic Editor: David B. Ordiz

Copyright © 2014 Lilia A. Cherdantseva et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. G. Fox and T. C. Wang, “Inflammation, atrophy, and gastric cancer,” The Journal of Clinical Investigation, vol. 117, no. 1, pp. 60–69, 2007. View at Publisher · View at Google Scholar · View at Scopus
  2. R. M. Genta and M. Rugge, “Assessing risks for gastric cancer: new tools for pathologists,” World Journal of Gastroenterology, vol. 12, no. 35, pp. 5622–5627, 2006. View at Google Scholar · View at Scopus
  3. J. A. Spitzer and J. J. Spitzer, “Lipopolysaccharide tolerance and ethanol modulate hepatic nitric oxide production in a gender-dependent manner,” Alcohol, vol. 21, no. 1, pp. 27–35, 2000. View at Publisher · View at Google Scholar · View at Scopus
  4. A. Zicari, G. Corrado, C. Pacchiarotti et al., “Cyclic vomiting syndrome: In vitro nitric oxide and interleukin-6 release by esophageal and gastric mucosa,” Digestive Diseases and Sciences, vol. 46, no. 4, pp. 831–835, 2001. View at Publisher · View at Google Scholar · View at Scopus
  5. A. Makristathis, E. Rokita, A. Labigne, B. Willinger, M. L. Rotter, and A. M. Hirschi, “Highly significant role of Helicobacter pylori urease in phagocytosis and production of oxygen metabolites by human granulocytes,” Journal of Infectious Diseases, vol. 177, no. 3, pp. 803–806, 1998. View at Publisher · View at Google Scholar · View at Scopus
  6. A. P. Gobert, B. D. Mersey, Y. Cheng, D. R. Blumberg, J. C. Newton, and K. T. Wilson, “Cutting edge: urease release by Helicobacter pylori stimulates macrophage inducible nitric oxide synthase,” Journal of Immunology, vol. 168, no. 12, pp. 6002–6006, 2002. View at Publisher · View at Google Scholar · View at Scopus
  7. A. P. Moran, “The role of lipopolysaccharide in Helicobacter pylori pathogenesis,” Alimentary Pharmacology & Therapeutics, vol. 10, supplement 1, pp. 39–50, 1996. View at Publisher · View at Google Scholar · View at Scopus
  8. M. Michetti, C. P. Kelly, J. P. Kraehenbuhl, H. Bouzourene, and P. Michetti, “Gastric mucosal α4β7-integrin-positive CD4 T lymphocytes and immune protection against Helicobacter infection in mice,” Gastroenterology, vol. 119, no. 1, pp. 109–118, 2000. View at Publisher · View at Google Scholar · View at Scopus
  9. L. I. Aruin, L. L. Kapuller, and V. A. Isakov, Morphological Diagnosis of Diseases of the Stomach and Intestines, Triada-Kh, Moscow, Russia, 1998.
  10. M. F. Dixon, R. M. Genta, J. H. Yardley et al., “Classification and grading of gastritis: the updated Sydney system,” The American Journal of Surgical Pathology, vol. 20, no. 10, pp. 1161–1181, 1996. View at Publisher · View at Google Scholar · View at Scopus
  11. E. R. Weibel, “Morphometry : stereological theory and practical methods,” in Models of Lung Disease: Microscopy and Structural Methods, pp. 199–252, Dekker, New York, NY, USA, 1990. View at Google Scholar
  12. P. Voland, D. L. Weeks, E. A. Marcus, C. Prinz, G. Sachs, and D. Scott, “Interactions among the seven Helicobacter pylori proteins encoded by the urease gene cluster,” American Journal of Physiology: Gastrointestinal and Liver Physiology, vol. 284, no. 1, pp. G96–G106, 2003. View at Publisher · View at Google Scholar · View at Scopus
  13. M. C. Gunn, J. C. Stephens, J. D. Stewart, and B. J. Rathbone, “Detection and typing of the virulence determinants cagA and vacA of Helicobacter pylori directly from biopsy DNA: are in vitro strains representative of in vivo strains?” European Journal of Gastroenterology and Hepatology, vol. 10, no. 8, pp. 683–687, 1998. View at Google Scholar · View at Scopus
  14. G. Rieder, W. Einsiedl, R. A. Hatz, M. Stolte, G. A. Enders, and A. Walz, “Comparison of CXC chemokines ENA-78 and interleukin-8 expression in Helicobacter pylori-associated gastritis,” Infection and Immunity, vol. 69, no. 1, pp. 81–88, 2001. View at Publisher · View at Google Scholar · View at Scopus
  15. N. Yoshida, D. N. Granger, D. J. Evans Jr. et al., “Mechanisms involved in Helicobacter pylori—induced inflammation,” Gastroenterology, vol. 105, no. 5, pp. 1431–1440, 1993. View at Publisher · View at Google Scholar · View at Scopus
  16. P. R. Harris, H. L. T. Mobley, G. I. Perez-Perez, M. J. Blaser, and P. D. Smith, “Helicobacter pylori urease is a potent stimulus of mononuclear phagocyte activation and inflammatory cytokine production,” Gastroenterology, vol. 111, no. 2, pp. 419–425, 1996. View at Publisher · View at Google Scholar · View at Scopus
  17. S. Hasegawa, S. Nishikawa, T. Miura et al., “Tumor necrosis factor-α is required for gastritis induced by Helicobacter felis infection in mice,” Microbial Pathogenesis, vol. 37, no. 3, pp. 119–124, 2004. View at Publisher · View at Google Scholar · View at Scopus
  18. N. D. Lewis, M. Asim, D. P. Barry et al., “Arginase II restricts host defense to Helicobacter pylori by attenuating inducible nitric oxide synthase translation in macrophages,” The Journal of Immunology, vol. 184, no. 5, pp. 2572–2582, 2010. View at Publisher · View at Google Scholar · View at Scopus
  19. C. Bogdan, “Nitric oxide and the immune response,” Nature Immunology, vol. 2, no. 10, pp. 907–916, 2001. View at Publisher · View at Google Scholar · View at Scopus