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Journal of Immunology Research
Volume 2015, Article ID 153132, 7 pages
Research Article

Detecting Genetic Associations between ATG5 and Lupus Nephritis by trans-eQTL

1Renal Division, Peking University First Hospital, Peking University Institute of Nephrology, Key Laboratory of Renal Disease, Ministry of Health of China and Key Laboratory of Chronic Kidney Disease Prevention and Treatment, Peking University, Ministry of Education, Beijing 100034, China
2Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, China

Received 21 April 2015; Revised 26 May 2015; Accepted 28 May 2015

Academic Editor: Fulvia Ceccarelli

Copyright © 2015 Yue-miao Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The supplementary materials have provide information about the association analyses between the positive trans-eSNPs genotypes and severity and outcome of LN patients and the bioinformation analyses of these trans-eSNPs in RegulomeDB and HaploReg v3 databases. As shown in Supplementary Table 1, no significant differences were observed between the clinical features and the different genotypes of the positive trans-eSNPs of ATG5. In Supplementary Table 2, the trans-SNPs with scores between 1 and 4 were listed and Supplementary Table 3 showed the scoring standard in RegulomeDB database. And searching by HaploReg v3, the regulatory effects of the positive trans-eSNPs and the SNPs in strong linkage disequilibrium (r2 ≥ 0.8) with them were shown in Supplementary Table 4.

  1. Supplementary Materials